Poeschla, Eric M.

A role for LEDGF/p75 in targeting HIV DNA integration

Ciuffi, A., Llano, M., Poeschla, E., Hoffmann, C., Leipzig, J., Shinn, P., Ecker, J. R., & Bushman, F. (2005) · Nature Medicine

HIV Research and TreatmentVirus-based gene therapy research

Cited by 658

An essential role for LEDGF/p75 in HIV integration

Llano, M., Saenz, D. T., Meehan, A., Wongthida, P., Peretz, M., Walker, W. H., Teo, W., & Poeschla, E. M. (2006) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 537

LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes

Llano, M., Vanegas, M., Fregoso, O., Saenz, D., Chung, S., Peretz, M., & Poeschla, E. M. (2004) · Journal of Virology

HIV Research and TreatmentVirus-based gene therapy research

Cited by 305

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

Sowd, G. A., Serrao, E., Wang, H., Wang, W., Fadel, H. J., Poeschla, E. M., & Engelman, A. N. (2016) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentVirus-based gene therapy research

Cited by 249

Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting

Marshall, H. M., Ronen, K., Berry, C., Llano, M., Sutherland, H., Saenz, D., Bickmore, W., Poeschla, E., & Bushman, F. D. (2007) · PLoS ONE

Virus-based gene therapy researchHIV Research and Treatment

Cited by 241

Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration

Achuthan, V., Perreira, J. M., Sowd, G. A., Puray-Chavez, M., McDougall, W. M., Paulucci-Holthauzen, A., Wu, X., Fadel, H. J., Poeschla, E. M., Multani, A. S., et al. (2018) · Cell Host & Microbe

HIV Research and TreatmentVirus-based gene therapy research

Cited by 205

Identification and Characterization of the Chromatin-binding Domains of the HIV-1 Integrase Interactor LEDGF/p75

Llano, M., Vanegas, M., Hutchins, N., Thompson, D., Delgado, S., & Poeschla, E. M. (2006) · Journal of Molecular Biology

HIV Research and TreatmentGenomics and Chromatin Dynamics

Cited by 199

A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

Sharma, A., Slaughter, A., Jena, N., Feng, L., Kessl, J. J., Fadel, H. J., Malani, N., Male, F., Wu, L., Poeschla, E., et al. (2014) · PLoS Pathogens

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 124

LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes

Singh, P. K., Plumb, M. R., Ferris, A. L., Iben, J. R., Wu, X., Fadel, H. J., Luke, B. T., Esnault, C., Poeschla, E. M., Hughes, S. H., et al. (2015) · Genes & Development

Virus-based gene therapy researchRNA Research and Splicing

Cited by 109

CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration

Li, W., Singh, P. K., Sowd, G. A., Bedwell, G. J., Jang, S., Achuthan, V., Oleru, A. V., Wong, D., Fadel, H. J., Lee, K., et al. (2020) · mBio

HIV Research and TreatmentVirus-based gene therapy research

Cited by 64

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors

Singh, P., Li, W., Bedwell, G., Fadel, H., Poeschla, E., & Engelman, A. (2022) · Viruses

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 13