Frezza, Christian

Extracellular vesicles are independent metabolic units with asparaginase activity

Iraci, N., Gaude, E., Leonardi, T., Costa, A. S. H., Cossetti, C., Peruzzotti-Jametti, L., Bernstock, J. D., Saini, H. K., Gelati, M., Vescovi, A. L., et al. (2017) · Nature Chemical Biology

Extracellular vesicles in diseaseAmino Acid Enzymes and Metabolism

Cited by 134

A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients

Rodenhizer, D., Gaude, E., Cojocari, D., Mahadevan, R., Frezza, C., Wouters, B. G., & McGuigan, A. P. (2016) · Nature Materials

Cancer, Hypoxia, and Metabolism3D Printing in Biomedical Research

Cited by 132

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells

Zheng, L., MacKenzie, E. D., Karim, S. A., Hedley, A., Blyth, K., Kalna, G., Watson, D. G., Szlosarek, P., Frezza, C., & Gottlieb, E. (2013) · Cancer & Metabolism

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 103

Metabolomic Profiling in Acute ST‐Segment–Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia–Reperfusion Injury

Kohlhauer, M., Dawkins, S., Costa, A. S. H., Lee, R., Young, T., Pell, V. R., Choudhury, R. P., Banning, A. P., Kharbanda, R. K., Study, O. A. M. I. (., et al. (2018) · Journal of the American Heart Association

Cardiac Ischemia and ReperfusionAcute Myocardial Infarction Research

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Fumarate hydratase loss promotes mitotic entry in the presence of DNA damage after ionising radiation

Johnson, T. I., Costa, A. S. H., Ferguson, A. N., & Frezza, C. (2018) · Cell Death & Disease

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 40

Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis

Ionescu, R.-B., Nicaise, A. M., Reisz, J. A., Williams, E. C., Prasad, P., Willis, C. M., Simões-Abade, M. B. C., Sbarro, L., Dzieciatkowska, M., Stephenson, D., et al. (2024) · Cell Stem Cell

Multiple Sclerosis Research StudiesTelomeres, Telomerase, and Senescence

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