DeFilippis, RosaAnna

Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia

McMahon, C. M., Ferng, T., Canaani, J., Wang, E. S., Morrissette, J. J. D., Eastburn, D. J., Pellegrino, M., Durruthy-Durruthy, R., Watt, C. D., Asthana, S., et al. (2019) · Cancer Discovery

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 446

Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes

Fordyce, C. A., Patten, K. T., Fessenden, T. B., DeFilippis, R., Hwang, E. S., Zhao, J., & Tlsty, T. D. (2012) · Breast Cancer Research

TGF-β signaling in diseasesTelomeres, Telomerase, and Senescence

Cited by 50

BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib

Leyte-Vidal, A., Garrido Ruiz, D., DeFilippis, R., Leske, I. B., Rea, D., Phan, S., Miller, K. B., Hu, F., Mase, A., Shan, Y., et al. (2024) · Blood

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 40

Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

Leyte-Vidal, A., DeFilippis, R., Outhwaite, I. R., Kwan, I., Lee, J. Y., Leavitt, C., Miller, K. B., Rea, D., Rangwala, A. M., Lou, K., et al. (2024) · Leukemia

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 17