Humpton, Timothy J.

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

DeNicola, G. M., Karreth, F. A., Humpton, T. J., Gopinathan, A., Wei, C., Frese, K., Mangal, D., Yu, K. H., Yeo, C. J., Calhoun, E. S., et al. (2011) · Nature

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 2,277

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Tajan, M., Hock, A. K., Blagih, J., Robertson, N. A., Labuschagne, C. F., Kruiswijk, F., Humpton, T. J., Adams, P. D., & Vousden, K. H. (2018) · Cell Metabolism

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 230

Oncogenic KRAS induces NIX-mediated mitophagy to promote pancreatic cancer

Humpton, T. J., Alagesan, B., DeNicola, G. M., Lu, D., Yordanov, G. N., Leonhardt, C. S., Yao, M. A., Alagesan, P., Zaatari, M. N., Park, Y., et al. (2019) · Cancer Discovery

Autophagy in Disease and TherapyPancreatic and Hepatic Oncology Research

Cited by 198

p53‐mediated adaptation to serine starvation is retained by a common tumour‐derived mutant

Humpton, T. J., Hock, A. K., Maddocks, O. D. K., & Vousden, K. H. (2018) · Cancer & Metabolism

Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism

Cited by 58