Durcan, Thomas M

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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The three ‘P’s of mitophagy: PARKIN.; PINK1.; and post-translational modifications

Durcan, T. M., & Fon, E. A. (2015) · Genes & Development

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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USP8 regulates mitophagy by removing K6‐linked ubiquitin conjugates from parkin

Durcan, T. M., Tang, M. Y., Pérusse, J. R., Dashti, E. A., Aguileta, M. A., McLelland, G., Gros, P., Shaler, T. A., Faubert, D., Coulombe, B., et al. (2014) · The EMBO Journal

Ubiquitin and proteasome pathwaysAutophagy in Disease and Therapy

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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72

Laflamme, C., McKeever, P. M., Kumar, R., Schwartz, J., Kolahdouzan, M., Chen, C. X., You, Z., Benaliouad, F., Gileadi, O., McBride, H. M., et al. (2019) · eLife

Amyotrophic Lateral Sclerosis ResearchMonoclonal and Polyclonal Antibodies Research

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TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress

Eldeeb, M. A., Bayne, A. N., Fallahi, A., Goiran, T., MacDougall, E. J., Soumbasis, A., Zorca, C. E., Tabah, J.-J., Thomas, R. A., Karpilovsky, N., et al. (2023) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 77

Rapid macropinocytic transfer of α-synuclein to lysosomes

Bayati, A., Banks, E., Han, C., Luo, W., Reintsch, W. E., Zorca, C. E., Shlaifer, I., Del Cid Pellitero, E., Vanderperre, B., McBride, H. M., et al. (2022) · Cell Reports

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 57

Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids

Cassel de Camps, C., Aslani, S., Stylianesis, N., Nami, H., Mohamed, N.-V., Durcan, T. M., & Moraes, C. (2022) · ACS Applied Bio Materials

Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications

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Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications

Ayoubi, R., Ryan, J., Biddle, M. S., Alshafie, W., Fotouhi, M., Bolivar, S. G., Ruiz Moleon, V., Eckmann, P., Worrall, D., McDowell, I., et al. (2023) · eLife

Monoclonal and Polyclonal Antibodies ResearchAdvanced Biosensing Techniques and Applications

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GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson’s disease

Senkevich, K., Zorca, C. E., Dworkind, A., Rudakou, U., Somerville, E., Yu, E., Ermolaev, A., Nikanorova, D., Ahmad, J., Ruskey, J. A., et al. (2023) · Brain

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

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The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology

Manecka, D.-L., Vanderperre, B., Fon, E. A., & Durcan, T. M. (2017) · Frontiers in Molecular Neuroscience

Parkinson's Disease Mechanisms and TreatmentsHeat shock proteins research

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