Vrieling, Harry

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, O., de Witte, C. J., Lõhmussaar, K., Valle-Inclan, J. E., Hami, N., Kester, L., Balgobind, A. V., Korving, J., Proost, N., Begthel, H., et al. (2019) · Nature Medicine

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

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Adverse outcome pathways: opportunities, limitations and open questions

Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S. H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., et al. (2017) · Archives of Toxicology

Animal testing and alternativesAgricultural safety and regulations

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The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions

Moser, J., Volker, M., Kool, H., Alekseev, S., Vrieling, H., Yasui, A., van Zeeland, A. A., & Mullenders, L. H. F. (2005) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

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Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation

Alekseev, S., Kool, H., Rebel, H., Fousteri, M., Moser, J., Backendorf, C., de Gruijl, F. R., Vrieling, H., & Mullenders, L. H. F. (2005) · Cancer Research

DNA Repair MechanismsSkin Protection and Aging

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Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

Hendriks, G., Calléja, F., Besaratinia, A., Vrieling, H., Pfeifer, G. P., Mullenders, L. H. F., Jansen, J. G., & de Wind, N. (2010) · Current Biology

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

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