Emrich, Thomas

Determination of critical quality attributes for monoclonal antibodies using quality by design principles

Alt, N., Zhang, T. Y., Motchnik, P., Taticek, R., Quarmby, V., Schlothauer, T., Beck, H., Emrich, T., & Harris, R. J. (2016) · Biologicals

Protein purification and stabilityBiosimilars and Bioanalytical Methods

Cited by 294

Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics

Schoch, A., Kettenberger, H., Mundigl, O., Winter, G., Engert, J., Heinrich, J., & Emrich, T. (2015) · Proceedings of the National Academy of Sciences

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 202

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Grevys, A., Frick, R., Mester, S., Flem-Karlsen, K., Nilsen, J., Foss, S., Sand, K. M. K., Emrich, T., Fischer, J. A. A., Greiff, V., et al. (2022) · iScience

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 51

Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology

Grathwohl, S., Quansah, E., Maroof, N., Steiner, J. A., Spycher, L., Benmansour, F., Duran-Pacheco, G., Siebourg-Polster, J., Oroszlan-Szovik, K., Remy, H., et al. (2020)

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 17