Wang, Bruce

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

The Tabula Muris Consortium, Almanzar, N., Antony, J., Baghel, A. S., Bakerman, I., Bansal, I., Barres, B. A., Beachy, P. A., Berdnik, D., Bilen, B., et al. (2020) · Nature

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The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

The Tabula Sapiens Consortium*, Jones, R. C., Karkanias, J., Krasnow, M. A., Pisco, A. O., Quake, S. R., Salzman, J., Yosef, N., Bulthaup, B., Brown, P., et al. (2022) · Science

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

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Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

Wang, B., Zhao, L., Fish, M., Logan, C. Y., & Nusse, R. (2015) · Nature

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

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Ageing hallmarks exhibit organ-specific temporal signatures

Schaum, N., Lehallier, B., Hahn, O., Pálovics, R., Hosseinzadeh, S., Lee, S. E., Sit, R., Lee, D. P., Losada, P. M., Zardeneta, M. E., et al. (2020) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

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Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria

Balwani, M., Sardh, E., Ventura, P., Peiró, P. A., Rees, D. C., Stölzel, U., Bissell, D. M., Bonkovsky, H. L., Windyga, J., Anderson, K. E., et al. (2020) · New England Journal of Medicine

Porphyrin Metabolism and DisordersNeonatal Health and Biochemistry

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Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

Malato, Y., Naqvi, S., Schürmann, N., Ng, R., Wang, B., Zape, J., Kay, M. A., Grimm, D., & Willenbring, H. (2011) · Journal of Clinical Investigation

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

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TWEAK induces liver progenitor cell proliferation

Jakubowski, A., Ambrose, C., Parr, M., Lincecum, J. M., Wang, M. Z., Zheng, T. S., Browning, B., Michaelson, J. S., Baestcher, M., Wang, B., et al. (2005) · Journal of Clinical Investigation

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

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Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

Peng, W. C., Logan, C. Y., Fish, M., Anbarchian, T., Aguisanda, F., Álvarez-Varela, A., Wu, P., Jin, Y., Zhu, J., Li, B., et al. (2018) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

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Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Zhang, M. J., Hou, K., Dey, K. K., Sakaue, S., Jagadeesh, K. A., Weinand, K., Taychameekiatchai, A., Rao, P., Pisco, A. O., Zou, J., et al. (2022) · Nature Genetics

Single-cell and spatial transcriptomicsGenetic Associations and Epidemiology

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Role of αvβ6 integrin in acute biliary fibrosis

Wang, B., Dolinski, B. M., Kikuchi, N., Leone, D. R., Peters, M. G., Weinreb, P. H., Violette, S. M., & Bissell, M. D. (2007) · Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

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Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Pálovics, R., Keller, A., Schaum, N., Tan, W., Fehlmann, T., Borja, M., Kern, F., Bonanno, L., Calcuttawala, K., Webber, J., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

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Cell types of origin of the cell-free transcriptome

Vorperian, S. K., Moufarrej, M. N., Tabula Sapiens Consortium, Overall Project Direction and Coordination, Jones, R. C., Karkanias, J., Krasnow, M., Pisco, A. O., Quake, S. R., Salzman, J., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

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Tissue Repair in the Mouse Liver Following Acute Carbon Tetrachloride Depends on Injury‐Induced Wnt/β‐Catenin Signaling

Zhao, L., Jin, Y., Donahue, K., Tsui, M., Fish, M., Logan, C. Y., Wang, B., & Nusse, R. (2019) · Hepatology

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

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TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis

Liang, B., Zhou, Y., Qian, M., Xu, M., Wang, J., Zhang, Y., Song, X., Wang, H., Lin, S., Ren, C., et al. (2021) · Journal of Hepatology

Wnt/β-catenin signaling in development and cancerHippo pathway signaling and YAP/TAZ

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