McBryan, Tony

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

Shah, P. P., Donahue, G., Otte, G. L., Capell, B. C., Nelson, D. M., Cao, K., Aggarwala, V., Cruickshanks, H. A., Rai, T. S., McBryan, T., et al. (2013) · Genes & Development

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 550

Senescent cells harbour features of the cancer epigenome

Cruickshanks, H. A., McBryan, T., Nelson, D. M., VanderKraats, N. D., Shah, P. P., van Tuyn, J., Singh Rai, T., Brock, C., Donahue, G., Dunican, D. S., et al. (2013) · Nature Cell Biology

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 358

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

Kennedy, A. L., Morton, J. P., Manoharan, I., Nelson, D. M., Jamieson, N. B., Pawlikowski, J. S., McBryan, T., Doyle, B., McKay, C., Oien, K. A., et al. (2011) · Molecular Cell

Telomeres, Telomerase, and SenescencePI3K/AKT/mTOR signaling in cancer

Cited by 213

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia

Rai, T. S., Cole, J. J., Nelson, D. M., Dikovskaya, D., Faller, W. J., Vizioli, M. G., Hewitt, R. N., Anannya, O., McBryan, T., Manoharan, I., et al. (2014) · Genes & Development

Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence

Cited by 162

Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape

Pchelintsev, N. A., McBryan, T., Rai, T. S., van Tuyn, J., Ray-Gallet, D., Almouzni, G., & Adams, P. D. (2013) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 143

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

Kennedy, A. L., McBryan, T., Enders, G. H., Johnson, F. B., Zhang, R., & Adams, P. D. (2010) · Cell Division

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 61