Bottlaender, Michel

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

Hamelin, L., Lagarde, J., Dorothée, G., Leroy, C., Labit, M., Comley, R. A., de Souza, L. C., Corne, H., Dauphinot, L., Bertoux, M., et al. (2016) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 519

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Jansen, W. J., Janssen, O., Tijms, B. M., Vos, S. J. B., Ossenkoppele, R., Visser, P. J., Amyloid Biomarker Study Group, Aarsland, D., Alcolea, D., Altomare, D., et al. (2022) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 290

Prevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia

Bergeron, D., Gorno‐Tempini, M. L., Rabinovici, G. D., Santos‐Santos, M. A., Seeley, W., Miller, B. L., Pijnenburg, Y., Keulen, M. A., Groot, C., van Berckel, B. N. M., et al. (2018) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 203

Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease

Hamelin, L., Lagarde, J., Dorothée, G., Potier, M. C., Corlier, F., Kuhnast, B., Caillé, F., Dubois, B., Fillon, L., Chupin, M., et al. (2018) · Brain

Neuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

Cited by 177

Increased microglial activation in patients with Parkinson disease using [18F]-DPA714 TSPO PET imaging

Lavisse, S., Goutal, S., Wimberley, C., Tonietto, M., Bottlaender, M., Gervais, P., Kuhnast, B., Peyronneau, M.-A., Barret, O., Lagarde, J., et al. (2021) · Parkinsonism & Related Disorders

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 127

Imaging Characteristics of Choroid Plexuses in Presymptomatic Multiple Sclerosis: A Retrospective Study

Ricigliano, V. A. G., Louapre, C., Poirion, E., Colombi, A., Yazdan Panah, A., Lazzarotto, A., Morena, E., Martin, E., Bottlaender, M., Bodini, B., et al. (2022) · Neurology Neuroimmunology & Neuroinflammation

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 64

Impact of Endothelial 18-kDa Translocator Protein on the Quantification of18F-DPA-714

Wimberley, C., Lavisse, S., Brulon, V., Peyronneau, M.-A., Leroy, C., Bodini, B., Remy, P., Stankoff, B., Buvat, I., & Bottlaender, M. (2018) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 63

In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates

Brouillet, E., Chavoix, C., Bottlaender, M., Khalili-Varasteh, M., Hantraye, P., Fournier, D., Dodd, R. H., & Mazière, M. (1991) · Brain Research

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 37

Distinct tau PET imaging patterns in typical and atypical Alzheimer’s disease

Sarazin, M., Lagarde, J., & Bottlaender, M. (2016) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 20

In Vivo High Intrinsic Efficacy of Triazolam: A Positron Emission Tomography Study in Nonhuman Primates

Bottlaender, M., Brouillet, E., Varastet, M., Le Breton, C., Schmid, L., Fuseau, C., Sitbon, R., Crouzel, C., & Mazière, M. (1994) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchSynthesis and pharmacology of benzodiazepine derivatives

Cited by 17

Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression

Corvo, C., Mendez-David, I., Goutal, S., Saba, W., Bottlaender, M., Caillé, F., Hen, R., Colle, R., Corruble, E., Tournier, N., et al. (2025) · ACS Pharmacology & Translational Science

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 7

Quantitative monitoring of ketamine’s impact on synaptic density using 11C-UCB-J PET imaging in the corticosterone mouse model of anxiety/depression

Corvo, C., Goutal, S., Mendez-David, I., Leterrier, S., Caille, F., Saba, W., Colle, R., Corruble, E., Lebon, V., Bottlaender, M., et al. (2026) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1