Yen, Hsin-Yung

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Liu, Y.-C., Yen, H.-Y., Chen, C.-Y., Chen, C.-H., Cheng, P.-F., Juan, Y.-H., Chen, C.-H., Khoo, K.-H., Yu, C.-J., Yang, P.-C., et al. (2011) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 424

PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

Yen, H.-Y., Hoi, K. K., Liko, I., Hedger, G., Horrell, M. R., Song, W., Wu, D., Heine, P., Warne, T., Lee, Y., et al. (2018) · Nature

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 284

Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins

Gault, J., Liko, I., Landreh, M., Shutin, D., Bolla, J. R., Jefferies, D., Agasid, M., Yen, H.-Y., Ladds, M. J. G. W., Lane, D. P., et al. (2020) · Nature Methods

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 171

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition

Yen, H.-Y., Liu, Y.-C., Chen, N.-Y., Tsai, C.-F., Wang, Y.-T., Chen, Y.-J., Hsu, T.-L., Yang, P.-C., & Wong, C.-H. (2015) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchLung Cancer Treatments and Mutations

Cited by 119

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors

Urner, L. H., Liko, I., Yen, H.-Y., Hoi, K.-K., Bolla, J. R., Gault, J., Almeida, F. G., Schweder, M.-P., Shutin, D., Ehrmann, S., et al. (2020) · Nature Communications

Lipid Membrane Structure and BehaviorMass Spectrometry Techniques and Applications

Cited by 107

Human glycogenins maintain glucose homeostasis by regulating glycogen metabolism

Weng, T.-H., Pien, Y.-C., Chen, C.-J., Chen, P.-P., Tseng, Y.-T., Chen, Y.-C., Hsiao, W.-P., Lee, Y.-T., Chen, Y.-A., Chen, Y.-C., et al. (2025) · Nature Communications

Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer

Cited by 9