Hanenberg, Helmut

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

Meindl, A., Hellebrand, H., Wiek, C., Erven, V., Wappenschmidt, B., Niederacher, D., Freund, M., Lichtner, P., Hartmann, L., Schaal, H., et al. (2010) · Nature Genetics

BRCA gene mutations in cancerDNA Repair Mechanisms

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Reid, S., Schindler, D., Hanenberg, H., Barker, K., Hanks, S., Kalb, R., Neveling, K., Kelly, P., Seal, S., Freund, M., et al. (2007) · Nature Genetics

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 642

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation

Fritsche, E., Schäfer, C., Calles, C., Bernsmann, T., Bernshausen, T., Wurm, M., Hübenthal, U., Cline, J. E., Hajimiragha, H., Schroeder, P., et al. (2007) · Proceedings of the National Academy of Sciences

Toxic Organic Pollutants ImpactSkin Protection and Aging

Cited by 437

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

Vaz, F., Hanenberg, H., Schuster, B., Barker, K., Wiek, C., Erven, V., Neveling, K., Endt, D., Kesterton, I., Autore, F., et al. (2010) · Nature Genetics

DNA Repair MechanismsBlood disorders and treatments

Cited by 408

The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

Levran, O., Attwooll, C., Henry, R. T., Milton, K. L., Neveling, K., Rio, P., Batish, S. D., Kalb, R., Velleuer, E., Barral, S., et al. (2005) · Nature Genetics

DNA Repair MechanismsBlood disorders and treatments

Cited by 370

Fanconi Anemia Proteins Function in Mitophagy and Immunity

Sumpter, R., Sirasanagandla, S., Fernández, Á. F., Wei, Y., Dong, X., Franco, L., Zou, Z., Marchal, C., Lee, M. Y., Clapp, D. W., et al. (2016) · Cell

Autophagy in Disease and TherapyDNA Repair Mechanisms

Cited by 250

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

Park, J.-Y., Singh, T. R., Nassar, N., Zhang, F., Freund, M., Hanenberg, H., Meetei, A. R., & Andreassen, P. R. (2014) · Oncogene

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 130

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G

Kailayangiri, S., Altvater, B., Spurny, C., Jamitzky, S., Schelhaas, S., Jacobs, A. H., Wiek, C., Roellecke, K., Hanenberg, H., Hartmann, W., et al. (2017) · OncoImmunology

Immune Cell Function and InteractionCAR-T cell therapy research

Cited by 104

Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1

Frauenstein, K., Sydlik, U., Tigges, J., Majora, M., Wiek, C., Hanenberg, H., Abel, J., Esser, C., Fritsche, E., Krutmann, J., et al. (2013) · Cell Death & Differentiation

Skin Protection and AgingCell death mechanisms and regulation

Cited by 56

Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model

Tonsing-Carter, E., Bailey, B. J., Saadatzadeh, M. R., Ding, J., Wang, H., Sinn, A. L., Peterman, K. M., Spragins, T. K., Silver, J. M., Sprouse, A. A., et al. (2015) · Molecular Cancer Therapeutics

Cancer-related Molecular PathwaysBreast Cancer Treatment Studies

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Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level

Skowron, M. A., Eul, K., Stephan, A., Ludwig, G. F., Wakileh, G. A., Bister, A., Söhngen, C., Raba, K., Petzsch, P., Poschmann, G., et al. (2022) · Molecular Oncology

Testicular diseases and treatmentsCancer Cells and Metastasis

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