Stegmann, Christian M.

Transcriptional and Cellular Diversity of the Human Heart

Tucker, N. R., Chaffin, M., Fleming, S. J., Hall, A. W., Parsons, V. A., Bedi, K. C., Akkad, A.-D., Herndon, C. N., Arduini, A., Papangeli, I., et al. (2020) · Circulation

Single-cell and spatial transcriptomicsCongenital heart defects research

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Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

Chaffin, M., Papangeli, I., Simonson, B., Akkad, A.-D., Hill, M. C., Arduini, A., Fleming, S. J., Melanson, M., Hayat, S., Kost-Alimova, M., et al. (2022) · Nature

Cardiac Fibrosis and RemodelingCardiomyopathy and Myosin Studies

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Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

Hillig, R. C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C. M., Werbeck, N. D., Briem, H., Boemer, U., Weiske, J., et al. (2019) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

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Deep learning enables genetic analysis of the human thoracic aorta

Pirruccello, J. P., Chaffin, M. D., Chou, E. L., Fleming, S. J., Lin, H., Nekoui, M., Khurshid, S., Friedman, S. F., Bick, A. G., Arduini, A., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyAortic Disease and Treatment Approaches

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