Muramatsu, Shin-ichi

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

Kadkhodaei, B., Ito, T., Joodmardi, E., Mattsson, B., Rouillard, C., Carta, M., Muramatsu, S.-I., Sumi-Ichinose, C., Nomura, T., Metzger, D., et al. (2009) · The Journal of Neuroscience

Nuclear Receptors and SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 382

A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson’s disease

Muramatsu, S.-I., Fujimoto, K.-I., Kato, S., Mizukami, H., Asari, S., Ikeguchi, K., Kawakami, T., Urabe, M., Kume, A., Sato, T., et al. (2010) · Molecular Therapy

Parkinson's Disease Mechanisms and TreatmentsVirus-based gene therapy research

Cited by 344

Gene Therapy for Aromatic l -Amino Acid Decarboxylase Deficiency

Hwu, W.-L., Muramatsu, S.-I., Tseng, S.-H., Tzen, K.-Y., Lee, N.-C., Chien, Y.-H., Snyder, R. O., Byrne, B. J., Tai, C.-H., & Wu, R.-M. (2012) · Science Translational Medicine

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 246

Efficacy and safety of AAV2 gene therapy in children with aromatic L-amino acid decarboxylase deficiency: an open-label, phase 1/2 trial

Chien, Y.-H., Lee, N.-C., Tseng, S.-H., Tai, C.-H., Muramatsu, S.-I., Byrne, B. J., & Hwu, W.-L. (2017) · The Lancet Child & Adolescent Health

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 142

Gene therapy improves motor and mental function of aromatic l-amino acid decarboxylase deficiency

Kojima, K., Nakajima, T., Taga, N., Miyauchi, A., Kato, M., Matsumoto, A., Ikeda, T., Nakamura, K., Kubota, T., Mizukami, H., et al. (2019) · Brain

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 139

YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

Tanaka, H., Homma, H., Fujita, K., Kondo, K., Yamada, S., Jin, X., Waragai, M., Ohtomo, G., Iwata, A., Tagawa, K., et al. (2020) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 119

Tau binding protein CAPON induces tau aggregation and neurodegeneration

Hashimoto, S., Matsuba, Y., Kamano, N., Mihira, N., Sahara, N., Takano, J., Muramatsu, S.-I., Saido, T. C., & Saito, T. (2019) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 111