Curnow, Kathleen M.

The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex

Curnow, K. M., Tusie-Luna, M.-T., Pascoe, L., Natarajan, R., Gu, J.-L., Nadler, J. L., & White, P. C. (1991) · Molecular Endocrinology

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 362

Disorders of Steroid 11β-Hydroxylase Isozymes*

WHITE, P. C., CURNOW, K. M., & PASCOE, L. (1994) · Endocrine Reviews

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 271

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.

Pascoe, L., Curnow, K. M., Slutsker, L., Connell, J. M., Speiser, P. W., New, M. I., & White, P. C. (1992) · Proceedings of the National Academy of Sciences

Hormonal Regulation and HypertensionRenin-Angiotensin System Studies

Cited by 271

Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency.

Pascoe, L., Curnow, K. M., Slutsker, L., Rösler, A., & White, P. C. (1992) · Proceedings of the National Academy of Sciences

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 188

The amino acid substitutions Ser288Gly and Val320Ala convert the cortisol producing enzyme, CYP11B1, into an aldosterone producing enzyme

Curnow, K. M., Mulatero, P., Emeric-Blanchouin, N., Aupetit-Faisant, B., Corvol, P., & Pascoe, L. (1997) · Nature Structural & Molecular Biology

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 102

Recombinant CYP11B Genes Encode Enzymes that Can Catalyze Conversion of 11-Deoxycortisol to Cortisol, 18-Hydroxycortisol, and 18-Oxocortisol1

Mulatero, P., Curnow, K. M., Aupetit-Faisant, B., Foekling, M., Gomez-Sanchez, C., Veglio, F., Jeunemaitre, X., Corvol, P., & Pascoe, L. (1998) · The Journal of Clinical Endocrinology & Metabolism

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 88

Deletion Hybrid Genes, due to Unequal Crossing Over between CYP11B1(11β-Hydroxylase) and CYP11B2(Aldosterone Synthase) Cause Steroid 11β-Hydroxylase Deficiency and Congenital Adrenal Hyperplasia1

Portrat, S., Mulatero, P., Curnow, K. M., Chaussain, J.-L., Morel, Y., & Pascoe, L. (2001) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 46