Kelly, Beth

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Tannahill, G. M., Curtis, A. M., Adamik, J., Palsson-McDermott, E. M., McGettrick, A. F., Goel, G., Frezza, C., Bernard, N. J., Kelly, B., Foley, N. H., et al. (2013) · Nature

Immune Response and InflammationImmune cells in cancer

Cited by 4,176

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Mills, E. L., Kelly, B., Logan, A., Costa, A. S. H., Varma, M., Bryant, C. E., Tourlomousis, P., Däbritz, J. H. M., Gottlieb, E., Latorre, I., et al. (2016) · Cell

Immune cells in cancerMitochondrial Function and Pathology

Cited by 2,291

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

Kelly, B., & O'Neill, L. A. (2015) · Cell Research

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 1,876

Mitochondria are the powerhouses of immunity

Mills, E. L., Kelly, B., & O'Neill, L. A. J. (2017) · Nature Immunology

Mitochondrial Function and PathologyImmune Response and Inflammation

Cited by 1,161

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages

Kelly, B., Tannahill, G. M., Murphy, M. P., & O'Neill, L. A. J. (2015) · Journal of Biological Chemistry

Inflammasome and immune disordersMetabolism, Diabetes, and Cancer

Cited by 334

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage

Cameron, A. M., Castoldi, A., Sanin, D. E., Flachsmann, L. J., Field, C. S., Puleston, D. J., Kyle, R. L., Patterson, A. E., Hässler, F., Buescher, J. M., et al. (2019) · Nature Immunology

Sirtuins and Resveratrol in MedicineImmune cells in cancer

Cited by 269

Beta-amyloid disrupted synaptic vesicle endocytosis in cultured hippocampal neurons

Kelly, B. L., & Ferreira, A. (2007) · Neuroscience

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 85