Machado, Roberto F.

Updated clinical classification of pulmonary hypertension

Simonneau, G., Gatzoulis, M. A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., Gomez Sanchez, M. A., Krishna Kumar, R., Landzberg, M., Machado, R. F., et al. (2013) · Journal of the American College of Cardiology

Pulmonary Hypertension Research and TreatmentsCongenital Heart Disease Studies

Cited by 4,191

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

Kato, G. J., McGowan, V., Machado, R. F., Little, J. A., Taylor, J., Morris, C. R., Nichols, J. S., Wang, X., Poljakovic, M., Morris, S. M., et al. (2006) · Blood

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 661

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

Villagra, J., Shiva, S., Hunter, L. A., Machado, R. F., Gladwin, M. T., & Kato, G. J. (2007) · Blood

Hemoglobinopathies and Related DisordersPlatelet Disorders and Treatments

Cited by 384

Diastolic Dysfunction Is an Independent Risk Factor for Death in Patients With Sickle Cell Disease

Sachdev, V., Machado, R. F., Shizukuda, Y., Rao, Y. N., Sidenko, S., Ernst, I., St. Peter, M., Coles, W. A., Rosing, D. R., Blackwelder, W. C., et al. (2007) · Journal of the American College of Cardiology

Hemoglobinopathies and Related DisordersCardiovascular Function and Risk Factors

Cited by 323

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

Hunter, C. J., Dejam, A., Blood, A. B., Shields, H., Kim-Shapiro, D. B., Machado, R. F., Tarekegn, S., Mulla, N., Hopper, A. O., Schechter, A. N., et al. (2004) · Nature Medicine

Pulmonary Hypertension Research and TreatmentsNeonatal Respiratory Health Research

Cited by 281

Mortality in Adults With Sickle Cell Disease and Pulmonary Hypertension

Mehari, A., Gladwin, M. T., Tian, X., Machado, R. F., & Kato, G. J. (2012) · JAMA

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 229

Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System Homeostasis

Tran, K. A., Zhang, X., Predescu, D., Huang, X., Machado, R. F., Göthert, J. R., Malik, A. B., Valyi-Nagy, T., & Zhao, Y.-Y. (2016) · Circulation

Barrier Structure and Function StudiesCell Adhesion Molecules Research

Cited by 219

N-Terminal Pro-Brain Natriuretic Peptide Levels and Risk of Death in Sickle Cell Disease

Machado, R. F., Anthi, A., Steinberg, M. H., Bonds, D., Sachdev, V., Kato, G. J., Taveira-DaSilva, A. M., Ballas, S. K., Blackwelder, W., Xu, X., et al. (2006) · JAMA

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 197

Echocardiographic Markers of Elevated Pulmonary Pressure and Left Ventricular Diastolic Dysfunction Are Associated With Exercise Intolerance in Adults and Adolescents With Homozygous Sickle Cell Anemia in the United States and United Kingdom

Sachdev, V., Kato, G. J., Gibbs, J. S. R., Barst, R. J., Machado, R. F., Nouraie, M., Hassell, K. L., Little, J. A., Schraufnagel, D. E., Krishnamurti, L., et al. (2011) · Circulation

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 147

Hemodynamic Predictors of Mortality in Adults with Sickle Cell Disease

Mehari, A., Alam, S., Tian, X., Cuttica, M. J., Barnett, C. F., Miles, G., Xu, D., Seamon, C., Adams-Graves, P., Castro, O. L., et al. (2013) · American Journal of Respiratory and Critical Care Medicine

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 135

Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom

Gladwin, M. T., Barst, R. J., Gibbs, J. S. R., Hildesheim, M., Sachdev, V., Nouraie, M., Hassell, K. L., Little, J. A., Schraufnagel, D. E., Krishnamurti, L., et al. (2014) · PLoS ONE

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 132

Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia

Saraf, S. L., Zhang, X., Kanias, T., Lash, J. P., Molokie, R. E., Oza, B., Lai, C., Rowe, J. H., Gowhari, M., Hassan, J., et al. (2014) · British Journal of Haematology

Hemoglobinopathies and Related DisordersChronic Kidney Disease and Diabetes

Cited by 120

Cerebrovascular disease associated with sickle cell pulmonary hypertension

Kato, G. J., Hsieh, M., Machado, R., Taylor, J., Little, J., Butman, J. A., Lehky, T., Tisdale, J., & Gladwin, M. T. (2006) · American Journal of Hematology

Hemoglobinopathies and Related DisordersPulmonary Hypertension Research and Treatments

Cited by 100

Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension

Chen, J., Sysol, J. R., Singla, S., Zhao, S., Yamamura, A., Valdez-Jasso, D., Abbasi, T., Shioura, K. M., Sahni, S., Reddy, V., et al. (2017) · Circulation

Pulmonary Hypertension Research and TreatmentsSirtuins and Resveratrol in Medicine

Cited by 86

Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study

Mack, A. K., McGowan II, V. R., Tremonti, C. K., Ackah, D., Barnett, C., Machado, R. F., Gladwin, M. T., & Kato, G. J. (2008) · British Journal of Haematology

Hemoglobinopathies and Related DisordersNitric Oxide and Endothelin Effects

Cited by 64