Poli, Valeria

Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice

Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., & Taub, R. (1996) · Science

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 1,536

The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

Poli, V. (1998) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 677

Interleukin 6 is required for the development of collagen-induced arthritis

Alonzi, T., Fattori, E., Lazzaro, D., Costa, P., Probert, L., Kollias, G., De Benedetti, F., Poli, V., & Ciliberto, G. (1998) · The Journal of Experimental Medicine

Rheumatoid Arthritis Research and TherapiesNatural Compounds in Disease Treatment

Cited by 604

Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation.

De Benedetti, F., Alonzi, T., Moretta, A., Lazzaro, D., Costa, P., Poli, V, Martini, A., Ciliberto, G., & Fattori, E. (1997) · Journal of Clinical Investigation

Growth Hormone and Insulin-like Growth FactorsCytokine Signaling Pathways and Interactions

Cited by 529

Defective inflammatory response in interleukin 6-deficient mice.

Fattori, E., Cappelletti, M., Costa, P., Sellitto, C., Cantoni, L., Carelli, M., Faggioni, R., Fantuzzi, G., Ghezzi, P., & Poli, V (1994) · The Journal of experimental medicine

Cytokine Signaling Pathways and InteractionsImmune Response and Inflammation

Cited by 525

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Priego, N., Zhu, L., Monteiro, C., Mulders, M., Wasilewski, D., Bindeman, W., Doglio, L., Martínez, L., Martínez-Saez, E., Ramón y Cajal, S., et al. (2018) · Nature Medicine

Brain Metastases and TreatmentGlioma Diagnosis and Treatment

Cited by 452

Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury

Hilfiker-Kleiner, D., Hilfiker, A., Fuchs, M., Kaminski, K., Schaefer, A., Schieffer, B., Hillmer, A., Schmiedl, A., Ding, Z., Podewski, E., et al. (2004) · Circulation Research

Cardiac Fibrosis and RemodelingCytokine Signaling Pathways and Interactions

Cited by 385

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

Bard-Chapeau, E. A., Li, S., Ding, J., Zhang, S. S., Zhu, H. H., Princen, F., Fang, D. D., Han, T., Bailly-Maitre, B., Poli, V., et al. (2011) · Cancer Cell

Protein Tyrosine PhosphatasesCytokine Signaling Pathways and Interactions

Cited by 332

Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver

Alonzi, T., Maritano, D., Gorgoni, B., Rizzuto, G., Libert, C., & Poli, V. (2001) · Molecular and Cellular Biology

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 329

Stat3 controls lysosomal-mediated cell death in vivo

Kreuzaler, P. A., Staniszewska, A. D., Li, W., Omidvar, N., Kedjouar, B., Turkson, J., Poli, V., Flavell, R. A., Clarkson, R. W. E., & Watson, C. J. (2011) · Nature Cell Biology

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 312

STAT3 Contributes to the Mitogenic Response of Hepatocytes during Liver Regeneration

Li, W., Liang, X., Kellendonk, C., Poli, V., & Taub, R. (2002) · Journal of Biological Chemistry

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 307

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.

Greenbaum, L. E., Li, W., Cressman, D. E., Peng, Y., Ciliberto, G., Poli, V, & Taub, R. (1998) · Journal of Clinical Investigation

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 270

The STAT3 isoforms α and β have unique and specific functions

Maritano, D., Sugrue, M. L., Tininini, S., Dewilde, S., Strobl, B., Fu, X., Murray-Tait, V., Chiarle, R., & Poli, V. (2004) · Nature Immunology

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 234

Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells

Fornek, J. L., Tygrett, L. T., Waldschmidt, T. J., Poli, V., Rickert, R. C., & Kansas, G. S. (2006) · Blood

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

Cited by 148

Constitutively active Stat3 enhances neu-mediated migration and metastasis in mammary tumors via upregulation of Cten

Barbieri, I., Pensa, S., Pannellini, T., Quaglino, E., Maritano, D., Demaria, M., Voster, A., Turkson, J., Cavallo, F., Watson, C. J., et al. (2010) · Cancer Research

Cytokine Signaling Pathways and InteractionsMechanisms of cancer metastasis

Cited by 148

In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway

Ledda-Columbano, G. M., Curto, M., Piga, R., Zedda, A. I., Menegazzi, M., Sartori, C., Shinozuka, H., Bluethmann, H., Poli, V, Ciliberto, G., et al. (1998) · Oncogene

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 96

Nucleocytoplasmic shuttling of persistently activated STAT3

Herrmann, A., Vogt, M., Mönnigmann, M., Clahsen, T., Sommer, U., Haan, S., Poli, V., Heinrich, P. C., & Müller-Newen, G. (2007) · Journal of Cell Science

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 94

The role of the N-terminal domain in dimerization and nucleocytoplasmic shuttling of latent STAT3

Vogt, M., Domoszlai, T., Kleshchanok, D., Lehmann, S., Schmitt, A., Poli, V., Richtering, W., & Müller-Newen, G. (2011) · Journal of Cell Science

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 80

Nucleus, mitochondrion, or reticulum? STAT3 à La Carte

Avalle, L., & Poli, V. (2018) · International Journal of Molecular Sciences

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 74

Stat3 isoforms, α and β, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3β mapping to its unique C-terminal end

Huang, Y., Qiu, J., Dong, S., Redell, M. S., Poli, V., Mancini, M. A., & Tweardy, D. J. (2007) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 65

IL-6, but not IFN-γ, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing

Regis, G., Icardi, L., Conti, L., Chiarle, R., Piva, R., Giovarelli, M., Poli, V, & Novelli, F. (2009) · Leukemia

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 47

Prevention of trauma/hemorrhagic shock-induced lung apoptosis by IL-6-mediated activation of Stat3

Moran, A., Tsimelzon, A. I., Mastrangelo, M. A., Wu, Y., Yu, B., Hilsenbeck, S. G., Poli, V., & Tweardy, D. J. (2009) · Clinical and Translational Science

Cytokine Signaling Pathways and InteractionsTrauma, Hemostasis, Coagulopathy, Resuscitation

Cited by 22

Autoimmune Myocarditis: Animal Models

Poli, V., Bruno, K. A., & Fairweather, D. (2020) · Myocarditis

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 5