Das, Atze T.

Optimization of the Tet-On system for regulated gene expression through viral evolution

Zhou, X., Vink, M., Klaver, B., Berkhout, B., & Das, A. T. (2006) · Gene Therapy

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 224

Reduced replication of human immunodeficiency virus type 1 mutants that use reverse transcription primers other than the natural tRNA(3Lys)

Das, A. T., Klaver, B., & Berkhout, B. (1995) · Journal of Virology

HIV Research and TreatmentRNA and protein synthesis mechanisms

Cited by 149

Viral Evolution as a Tool to Improve the Tetracycline-regulated Gene Expression System

Das, A. T., Zhou, X., Vink, M., Klaver, B., Verhoef, K., Marzio, G., & Berkhout, B. (2004) · Journal of Biological Chemistry

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 129

A conserved hairpin structure predicted for the poly(A) signal of human and simian immunodeficiency viruses

Berkhout, B., Klaver, B., & Das, A. T. (1995) · Virology

RNA Research and SplicingHIV Research and Treatment

Cited by 57

A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses

Chtarto, A., Humbert-Claude, M., Bockstael, O., Das, A. T., Boutry, S., Breger, L. S., Klaver, B., Melas, C., Barroso-Chinea, P., Gonzalez-Hernandez, T., et al. (2016) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 43

Selecting the optimal Tet‐On system for doxycycline‐inducible gene expression in transiently transfected and stably transduced mammalian cells

Das, A. T., Zhou, X., Metz, S. W., Vink, M. A., & Berkhout, B. (2016) · Biotechnology Journal

Virus-based gene therapy researchGene Regulatory Network Analysis

Cited by 36

Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo.

Centlivre, M., Zhou, X., Pouw, S. M., Weijer, K., Kleibeuker, W., Das, A. T., Blom, B., Seppen, J., Berkhout, B., & Legrand, N. (2010) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 30

A Sensitive Cell-Based Assay to Measure the Doxycycline Concentration in Biological Samples

Kleibeuker, W., Zhou, X., Centlivre, M., Legrand, N., Page, M., Almond, N., Berkhout, B., & Das, A. T. (2009) · Human Gene Therapy

bioluminescence and chemiluminescence researchAnalytical Methods in Pharmaceuticals

Cited by 20

Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

Manoussaka, M. S., Berry, N., Ferguson, D., Stebbings, R., Robinson, M., Ham, C., Page, M., Li, B., Das, A. T., Berkhout, B., et al. (2013) · Retrovirology

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 16

Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1

Kiselyeva, Y., Ito, Y., Lima, R. G., Grivel, J.-C., Das, A. T., Berkhout, B., & Margolis, L. B. (2004) · Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 13

A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion

Legrand, N., van der Velden, G. J., Fang, R. H. T., Douaisi, M., Weijer, K., Das, A. T., Blom, B., Uittenbogaart, C. H., Berkhout, B., & Centlivre, M. (2012) · Journal of General Virology

HIV Research and TreatmentVirus-based gene therapy research

Cited by 8

Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements

van der Velden, Y. U., Kleibeuker, W., Harwig, A., Klaver, B., Siteur-van Rijnstra, E., Frankin, E., Berkhout, B., & Das, A. T. (2016) · Virology

HIV Research and TreatmentVirus-based gene therapy research

Cited by 3