Plouffe, Steven W.

Differential regulation of mTORC1 by leucine and glutamine

Jewell, J. L., Kim, Y. C., Russell, R. C., Yu, F.-X., Park, H. W., Plouffe, S. W., Tagliabracci, V. S., & Guan, K.-L. (2015) · Science

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

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RAP2 mediates mechanoresponses of the Hippo pathway

Meng, Z., Qiu, Y., Lin, K. C., Kumar, A., Placone, J. K., Fang, C., Wang, K.-C., Lu, S., Pan, M., Hong, A. W., et al. (2018) · Nature

Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions

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Characterization of Hippo Pathway Components by Gene Inactivation

Plouffe, S. W., Meng, Z., Lin, K. C., Lin, B., Hong, A. W., Chun, J. V., & Guan, K.-L. (2016) · Molecular Cell

Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics

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The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1

Hansen, C. G., Ng, Y. L. D., Lam, W.-L. M., Plouffe, S. W., & Guan, K.-L. (2015) · Cell Research

Hippo pathway signaling and YAP/TAZPI3K/AKT/mTOR signaling in cancer

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YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

Yu, O. M., Benitez, J. A., Plouffe, S. W., Ryback, D., Klein, A., Smith, J., Greenbaum, J., Delatte, B., Rao, A., Guan, K.-L., et al. (2018) · Oncogene

Hippo pathway signaling and YAP/TAZGlioma Diagnosis and Treatment

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