Bürckstümmer, Tilmann

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Bürckstümmer, T., Baumann, C., Blüml, S., Dixit, E., Dürnberger, G., Jahn, H., Planyavsky, M., Bilban, M., Colinge, J., Bennett, K. L., et al. (2009) · Nature Immunology

Inflammasome and immune disordersinterferon and immune responses

Cited by 1,091

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Hantschel, O., Rix, U., Schmidt, U., Bürckstümmer, T., Kneidinger, M., Schütze, G., Colinge, J., Bennett, K. L., Ellmeier, W., Valent, P., et al. (2007) · Proceedings of the National Academy of Sciences

Chronic Myeloid Leukemia TreatmentsMast cells and histamine

Cited by 284

Viral immune modulators perturb the human molecular network by common and unique strategies

Pichlmair, A., Kandasamy, K., Alvisi, G., Mulhern, O., Sacco, R., Habjan, M., Binder, M., Stefanovic, A., Eberle, C.-A., Goncalves, A., et al. (2012) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 262

Biological plasticity rescues target activity in CRISPR knock outs

Smits, A. H., Ziebell, F., Joberty, G., Zinn, N., Mueller, W. F., Clauder-Münster, S., Eberhard, D., Fälth Savitski, M., Grandi, P., Jakob, P., et al. (2019) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 219

Functional Dissection of the TBK1 Molecular Network

Goncalves, A., Bürckstümmer, T., Dixit, E., Scheicher, R., Górna, M. W., Karayel, E., Sugar, C., Stukalov, A., Berg, T., Kralovics, R., et al. (2011) · PLoS ONE

interferon and immune responsesNF-κB Signaling Pathways

Cited by 136

Initial characterization of the human central proteome

Burkard, T. R., Planyavsky, M., Kaupe, I., Breitwieser, F. P., Bürckstümmer, T., Bennett, K. L., Superti-Furga, G., & Colinge, J. (2011) · BMC Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 67

Parallel reverse genetic screening in mutant human cells using transcriptomics

Gapp, B. V., Konopka, T., Penz, T., Dalal, V., Bürckstümmer, T., Bock, C., & Nijman, S. M. (2016) · Molecular Systems Biology

Genomics and Rare DiseasesBioinformatics and Genomic Networks

Cited by 12