Cheng, Feixiong

Adverse drug events: database construction and in silico prediction

Cheng, F., Li, W., Wang, X., Zhou, Y., Wu, Z., Shen, J., & Tang, Y. (2013) · Journal of Chemical Information and Modeling

Pharmacovigilance and Adverse Drug ReactionsComputational Drug Discovery Methods

Cited by 124

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease

Xu, J., Mao, C., Hou, Y., Luo, Y., Binder, J. L., Zhou, Y., Bekris, L. M., Shin, J., Hu, M., Wang, F., et al. (2022) · Cell Reports

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 115

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

Lu, W., Yu, W., He, J., Liu, W., Yang, J., Lin, X., Zhang, Y., Wang, X., Jiang, W., Luo, J., et al. (2021) · EMBO Molecular Medicine

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 112

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

Carling, G. K., Fan, L., Foxe, N. R., Norman, K., Wong, M. Y., Zhu, D., Corona, C., Razzoli, A., Yu, F., Yarahmady, A., et al. (2024) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 89

Artificial intelligence for drug discovery and development in Alzheimer's disease

Qiu, Y., & Cheng, F. (2024) · Current Opinion in Structural Biology

Computational Drug Discovery MethodsAlzheimer's disease research and treatments

Cited by 83

High-throughput target trial emulation for Alzheimer’s disease drug repurposing with real-world data

Zang, C., Zhang, H., Xu, J., Zhang, H., Fouladvand, S., Havaldar, S., Cheng, F., Chen, K., Chen, Y., Glicksberg, B. S., et al. (2023) · Nature Communications

Advanced Causal Inference TechniquesAlzheimer's disease research and treatments

Cited by 69

Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer’s disease

Cheng, F., Wang, F., Tang, J., Zhou, Y., Fu, Z., Zhang, P., Haines, J. L., Leverenz, J. B., Gan, L., Hu, J., et al. (2024) · Cell Reports Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease

Qiu, Y., Hou, Y., Gohel, D., Zhou, Y., Xu, J., Bykova, M., Yang, Y., Leverenz, J. B., Pieper, A. A., Nussinov, R., et al. (2024) · Cell Reports

Alzheimer's disease research and treatmentsGut microbiota and health

Cited by 40

The Alzheimer's Cell Atlas (TACA): A single‐cell molecular map for translational therapeutics accelerator in Alzheimer's disease

Zhou, Y., Xu, J., Hou, Y., Bekris, L., Leverenz, J. B., Pieper, A. A., Cummings, J., & Cheng, F. (2022) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Alzheimer's disease research and treatmentsSingle-cell and spatial transcriptomics

Cited by 39

Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease

Gupta, C., Xu, J., Jin, T., Khullar, S., Liu, X., Alatkar, S., Cheng, F., & Wang, D. (2022) · PLOS Computational Biology

Gene Regulatory Network AnalysisAlzheimer's disease research and treatments

Cited by 33

Critical evaluation of real‐world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

Tonegawa‐Kuji, R., Karavani, E., Danziger, M., Zhang, P., Hou, Y., Zhou, Y., Bykova, M., Pieper, A. A., Rosen‐Zvi, M., Cummings, J., et al. (2026) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 1