Singer, Mervyn

The third international consensus definitions for sepsis and septic shock (Sepsis-3).

Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J.-D., Coopersmith, C. M., et al. (2016) · JAMA

Sepsis Diagnosis and TreatmentInflammation biomarkers and pathways

Cited by 28,250

Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.

Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine

Sepsis Diagnosis and TreatmentAbdominal Surgery and Complications

Cited by 6,621

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., Scherag, A., Rubenfeld, G., Kahn, J. M., Shankar-Hari, M., Singer, M., et al. (2016) · JAMA

Sepsis Diagnosis and TreatmentInflammation biomarkers and pathways

Cited by 3,939

Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.

Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Critical Care Medicine

Sepsis Diagnosis and TreatmentAbdominal Surgery and Complications

Cited by 3,652

Trial of early, goal-directed resuscitation for septic shock.

Mouncey, P. R., Osborn, T. M., Power, G. S., Harrison, D. A., Sadique, M. Z., Grieve, R. D., Jahan, R., Harvey, S. E., Bell, D., Bion, J. F., et al. (2015) · New England Journal of Medicine

Sepsis Diagnosis and TreatmentHemodynamic Monitoring and Therapy

Cited by 1,604

Prevalence and outcomes of infection among patients in intensive care units in 2017.

Vincent, J.-L., Sakr, Y., Singer, M., Martin-Loeches, I., Machado, F. R., Marshall, J. C., Finfer, S., Pelosi, P., Brazzi, L., Aditianingsih, D., et al. (2020) · JAMA

Nosocomial Infections in ICUSepsis Diagnosis and Treatment

Cited by 1,011

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine

Marik, P. E., Pastores, S. M., Annane, D., Meduri, G. U., Sprung, C. L., Arlt, W., Keh, D., Briegel, J., Beishuizen, A., Dimopoulou, I., et al. (2008) · Critical Care Medicine

Adrenal Hormones and DisordersHyperglycemia and glycemic control in critically ill and hospitalized patients

Cited by 912

Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial

Girardis, M., Busani, S., Damiani, E., Donati, A., Rinaldi, L., Marudi, A., Morelli, A., Antonelli, M., & Singer, M. (2016) · JAMA

Respiratory Support and MechanismsSepsis Diagnosis and Treatment

Cited by 723

Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis

Gordon, A. C., Perkins, G. D., Singer, M., McAuley, D. F., Orme, R. M. L., Santhakumaran, S., Mason, A. J., Cross, M., Al-Beidh, F., Best-Lane, J., et al. (2016) · New England Journal of Medicine

Sepsis Diagnosis and TreatmentAntibiotics Pharmacokinetics and Efficacy

Cited by 372

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

Cochemé, H. M., Quin, C., McQuaker, S. J., Cabreiro, F., Logan, A., Prime, T. A., Abakumova, I., Patel, J. V., Fearnley, I. M., James, A. M., et al. (2011) · Cell Metabolism

Redox biology and oxidative stressGenetics, Aging, and Longevity in Model Organisms

Cited by 313

Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit

Shulman, R., Singer, M., Goldstone, J., & Bellingan, G. (2005) · Critical Care

Patient Safety and Medication ErrorsElectronic Health Records Systems

Cited by 252

Antibiotics for sepsis-finding the equilibrium.

Klompas, M., Calandra, T., & Singer, M. (2018) · JAMA

Sepsis Diagnosis and TreatmentAntibiotics Pharmacokinetics and Efficacy

Cited by 183

Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis: The ADAPT-Sepsis Randomized Clinical Trial

Dark, P., Hossain, A., McAuley, D. F., Brealey, D., Carlson, G., Clayton, J. C., Felton, T. W., Ghuman, B. K., Gordon, A. C., Hellyer, T. P., et al. (2025) · JAMA

Sepsis Diagnosis and TreatmentAntibiotics Pharmacokinetics and Efficacy

Cited by 114

Multicenter comparison of cortisol as measured by different methods in samples of patients with septic shock

for the CORTICUS Study Group, Briegel, J., Sprung, C. L., Annane, D., Singer, M., Keh, D., Moreno, R., Möhnle, P., Weiss, Y., Avidan, A., et al. (2009) · Intensive Care Medicine

Adrenal Hormones and DisordersClinical Laboratory Practices and Quality Control

Cited by 93

Prediction of Complications and Prognostication in Perioperative Medicine: A Systematic Review and PROBAST Assessment of Machine Learning Tools

Arina, P., Kaczorek, M. R., Hofmaenner, D. A., Pisciotta, W., Refinetti, P., Singer, M., Mazomenos, E. B., & Whittle, J. (2024) · Anesthesiology

Cardiac, Anesthesia and Surgical OutcomesArtificial Intelligence in Healthcare and Education

Cited by 81

Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study

Ehler, J., Barrett, L. K., Taylor, V., Groves, M., Scaravilli, F., Wittstock, M., Kolbaske, S., Grossmann, A., Henschel, J., Gloger, M., et al. (2017) · Critical Care

Sepsis Diagnosis and TreatmentIntensive Care Unit Cognitive Disorders

Cited by 80

Impact on mortality of prompt admission to critical care for deteriorating ward patients: An instrumental variable analysis using critical care bed strain.

Harris, S., Singer, M., Sanderson, C., Grieve, R., Harrison, D., & Rowan, K. (2018) · Intensive Care Medicine

Emergency and Acute Care StudiesHospital Admissions and Outcomes

Cited by 79

Tissue oxygen tension monitoring of organ perfusion: rationale, methodologies, and literature review

De Santis, V., & Singer, M. (2015) · British Journal of Anaesthesia

Hemodynamic Monitoring and TherapyOptical Imaging and Spectroscopy Techniques

Cited by 64

Changes in CRH and ACTH Synthesis during Experimental and Human Septic Shock

Polito, A., Sonneville, R., Guidoux, C., Barrett, L., Viltart, O., Mattot, V., Siami, S., Lorin de la Grandmaison, G., Chrétien, F., Singer, M., et al. (2011) · PLoS ONE

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 55

Effect of antibiotic discontinuation strategies on mortality and infectious complications in critically ill septic patients: A meta-analysis and trial sequential analysis.

Arulkumaran, N., Khpal, M., Tam, K., Baheerathan, A., Corredor, C., & Singer, M. (2020) · Critical Care Medicine

Sepsis Diagnosis and TreatmentAntibiotic Use and Resistance

Cited by 36

Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Pottecher, J., Adamopoulos, C., Lejay, A., Bouitbir, J., Charles, A.-L., Meyer, A., Singer, M., Wolff, V., Diemunsch, P., Laverny, G., et al. (2018) · Frontiers in Physiology

Cardiac Ischemia and ReperfusionCell death mechanisms and regulation

Cited by 33

Neuroprotective effects of ammonium tetrathiomolybdate, a slow-release sulfide donor, in a rodent model of regional stroke

Mendonça, B. P., Cardoso, J. D. S., Michels, M., Vieira, A. C., Wendhausen, D., Manfredini, A., Singer, M., Dal-Pizzol, F., & Dyson, A. (2020) · Intensive Care Medicine Experimental

Neuroprotection in Cerebral IschemiaAcute Ischemic Stroke Management

Cited by 21

Sepsis - the broken code how accurately is sepsis being diagnosed?

Tidswell, R., Parker, T., Brealey, D., & Singer, M. (2020) · Journal of Infection

Sepsis Diagnosis and TreatmentClinical Reasoning and Diagnostic Skills

Cited by 13