Gkogkas, Christos G.

Autism-related deficits via dysregulated eIF4E-dependent translational control

Gkogkas, C. G., Khoutorsky, A., Ran, I., Rampakakis, E., Nevarko, T., Weatherill, D. B., Vasuta, C., Yee, S., Truitt, M., Dallaire, P., et al. (2013) · Nature

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 522

mRNA helicases: the tacticians of translational control

Parsyan, A., Svitkin, Y., Shahbazian, D., Gkogkas, C., Lasko, P., Merrick, W. C., & Sonenberg, N. (2011) · Nature Reviews Molecular Cell Biology

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 323

Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes

Gkogkas, C. G., Khoutorsky, A., Cao, R., Jafarnejad, S. M., Prager-Khoutorsky, M., Giannakas, N., Kaminari, A., Fragkouli, A., Nader, K., Price, T. J., et al. (2014) · Cell Reports

Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms

Cited by 201

Microglia-mediated degradation of perineuronal nets promotes pain

Tansley, S., Gu, N., Guzmán, A. U., Cai, W., Wong, C., Lister, K. C., Muñoz-Pino, E., Yousefpour, N., Roome, R. B., Heal, J., et al. (2022) · Science

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 195

Autistic-like Behavior and Cerebellar Dysfunction in Bmal1 Mutant Mice Ameliorated by mTORC1 Inhibition

Liu, D., Nanclares, C., Simbriger, K., Fang, K., Lorsung, E., Le, N., Amorim, I. S., Chalkiadaki, K., Pathak, S. S., Li, J., et al. (2023) · Molecular Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 56

Induction of an Alternative mRNA 5′ Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection

Hoang, H.-D., Graber, T. E., Jia, J.-J., Vaidya, N., Gilchrist, V. H., Xiang, X., Li, W., Cowan, K. N., Gkogkas, C. G., Jaramillo, M., et al. (2019) · Cell Reports

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 18

Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

Lister, K. C., Wong, C., Uttam, S., Parisien, M., Stecum, P., Brown, N., Cai, W., Ho-Tieng, D., Hooshmandi, M., Gu, N., et al. (2026) · eLife

Pain Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research

Cited by 2