Hotta, Akitsu

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

Kattman, S. J., Witty, A. D., Gagliardi, M., Dubois, N. C., Niapour, M., Hotta, A., Ellis, J., & Keller, G. (2011) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 1,159

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Xu, H., Wang, B., Ono, M., Kagita, A., Fujii, K., Sasakawa, N., Ueda, T., Gee, P., Nishikawa, M., Nomura, M., et al. (2019) · Cell stem cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 581

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

Cheung, A. Y. L., Horvath, L. M., Grafodatskaya, D., Pasceri, P., Weksberg, R., Hotta, A., Carrel, L., & Ellis, J. (2011) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersPluripotent Stem Cells Research

Cited by 271

Delivery of CRISPR-Cas tools for in vivo genome editing therapy: Trends and challenges

Taha, E. A., Lee, J., & Hotta, A. (2022) · Journal of Controlled Release

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 259

Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells

Wang, B., Iriguchi, S., Waseda, M., Ueda, N., Ueda, T., Xu, H., Minagawa, A., Ishikawa, A., Yano, H., Ishi, T., et al. (2021) · Nature Biomedical Engineering

Pluripotent Stem Cells ResearchCAR-T cell therapy research

Cited by 189

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy

Rastegar, M., Hotta, A., Pasceri, P., Makarem, M., Cheung, A. Y. L., Elliott, S., Park, K. J., Adachi, M., Jones, F. S., Clarke, I. D., et al. (2009) · PLoS ONE

Virus-based gene therapy researchGenetics and Neurodevelopmental Disorders

Cited by 79