Jaimon, Ebsy

Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., & Pfeffer, S. R. (2023) · eLife

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 76

Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease

Khan, S. S., Jaimon, E., Lin, Y.-E., Nikoloff, J., Tonelli, F., Alessi, D. R., & Pfeffer, S. R. (2024) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsGenetic and Kidney Cyst Diseases

Cited by 61

Parkinson’s VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B

Pal, P., Taylor, M., Lam, P. Y., Tonelli, F., Hecht, C. A., Lis, P., Nirujogi, R. S., Phung, T. K., Yeshaw, W. M., Jaimon, E., et al. (2023) · Science Advances

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 36

Insights into cargo sorting by SNX32 in neuronal and non-neuronal cells: physiological implications in neurite outgrowth

Sugatha, J., Priya, A., Raj, P., Jaimon, E., Jose, A., & Datta, S. (2022) · eLife

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 19

Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons

Lin, Y.-E., Jaimon, E., Tonelli, F., & Pfeffer, S. R. (2025) · Life Science Alliance

Parkinson's Disease Mechanisms and TreatmentsGenetic and Kidney Cyst Diseases

Cited by 16