Orthwein, Alexandre

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

Fradet-Turcotte, A., Canny, M. D., Escribano-Díaz, C., Orthwein, A., Leung, C. C. Y., Huang, H., Landry, M.-C., Kitevski-LeBlanc, J., Noordermeer, S. M., Sicheri, F., et al. (2013) · Nature

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 686

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

Polak, P., Kim, J., Braunstein, L. Z., Karlic, R., Haradhavala, N. J., Tiao, G., Rosebrock, D., Livitz, D., Kübler, K., Mouw, K. W., et al. (2017) · Nature Genetics

BRCA gene mutations in cancerCancer Genomics and Diagnostics

Cited by 531

RETRACTED ARTICLE: A mechanism for the suppression of homologous recombination in G1 cells

Orthwein, A., Noordermeer, S. M., Wilson, M. D., Landry, S., Enchev, R. I., Sherker, A., Munro, M., Pinder, J., Salsman, J., Dellaire, G., et al. (2015) · Nature

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 471