Splinter, Patrick L.

Up-regulation of microRNA 506 leads to decreased Cl−/HCO3 − anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis

Banales, J. M., Sáez, E., Úriz, M., Sarvide, S., Urribarri, A. D., Splinter, P., Tietz Bogert, P. S., Bujanda, L., Prieto, J., Medina, J. F., et al. (2012) · Hepatology

Liver Diseases and ImmunityMicroRNA in disease regulation

Cited by 250

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

Tabibian, J. H., O'Hara, S. P., Splinter, P. L., Trussoni, C. E., & LaRusso, N. F. (2014) · Hepatology

Liver Diseases and ImmunityTelomeres, Telomerase, and Senescence

Cited by 241

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

Tabibian, J. H., O'Hara, S. P., Trussoni, C. E., Tietz, P. S., Splinter, P. L., Mounajjed, T., Hagey, L. R., & LaRusso, N. F. (2016) · Hepatology

Liver Diseases and ImmunityGut microbiota and health

Cited by 223

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Guicciardi, M. E., Trussoni, C. E., Krishnan, A., Bronk, S. F., Lorenzo Pisarello, M. J., O'Hara, S. P., Splinter, P. L., Gao, Y., Vig, P., Revzin, A., et al. (2018) · Journal of Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 183

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y 12 purinergic receptors

Masyuk, A. I., Gradilone, S. A., Banales, J. M., Huang, B. Q., Masyuk, T. V., Lee, S.-O., Splinter, P. L., Stroope, A. J., & LaRusso, N. F. (2008) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Genetic and Kidney Cyst DiseasesAdenosine and Purinergic Signaling

Cited by 170

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

Masyuk, A. I., Huang, B. Q., Radtke, B. N., Gajdos, G. B., Splinter, P. L., Masyuk, T. V., Gradilone, S. A., & LaRusso, N. F. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Drug Transport and Resistance MechanismsGenetic and Kidney Cyst Diseases

Cited by 143

Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/− ) mice

Moncsek, A., Al‐Suraih, M. S., Trussoni, C. E., O'Hara, S. P., Splinter, P. L., Zuber, C., Patsenker, E., Valli, P. V., Fingas, C. D., Weber, A., et al. (2018) · Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 136