Shusta, Eric V.

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

Helms, H. C., Abbott, N. J., Burek, M., Cecchelli, R., Couraud, P.-O., Deli, M. A., Förster, C., Galla, H. J., Romero, I. A., Shusta, E. V., et al. (2016) · Journal of Cerebral Blood Flow & Metabolism

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 843

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Lippmann, E. S., Azarin, S. M., Kay, J. E., Nessler, R. A., Wilson, H. K., Al-Ahmad, A., Palecek, S. P., & Shusta, E. V. (2012) · Nature Biotechnology

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 800

Blood–Brain Barrier Transport of Therapeutics via Receptor-Mediation

Jones, A. R., & Shusta, E. V. (2007) · Pharmaceutical Research

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 549

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Lippmann, E. S., Al-Ahmad, A., Azarin, S. M., Palecek, S. P., & Shusta, E. V. (2014) · Scientific Reports

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 508

Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier

Lajoie, J. M., & Shusta, E. V. (2015) · Annual Review of Pharmacology and Toxicology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 399

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells

Qian, T., Maguire, S. E., Canfield, S. G., Bao, X., Olson, W. R., Shusta, E. V., & Palecek, S. P. (2017) · Science Advances

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 254

An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells

Canfield, S. G., Stebbins, M. J., Morales, B. S., Asai, S. W., Vatine, G. D., Svendsen, C. N., Palecek, S. P., & Shusta, E. V. (2017) · Journal of Neurochemistry

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 250

Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier

Vatine, G. D., Al-Ahmad, A., Barriga, B. K., Svendsen, S., Salim, A., Garcia, L., Garcia, V. J., Ho, R., Yucer, N., Qian, T., et al. (2017) · Cell Stem Cell

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 233

Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties

Stebbins, M. J., Gastfriend, B. D., Canfield, S. G., Lee, M.-S., Richards, D., Faubion, M. G., Li, W.-J., Daneman, R., Palecek, S. P., & Shusta, E. V. (2019) · Science Advances

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 195

Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells

Stebbins, M. J., Wilson, H. K., Canfield, S. G., Qian, T., Palecek, S. P., & Shusta, E. V. (2016) · Methods

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 179

Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells

Wilson, H. K., Canfield, S. G., Hjortness, M. K., Palecek, S. P., & Shusta, E. V. (2015) · Fluids and Barriers of the CNS

Barrier Structure and Function StudiesPluripotent Stem Cells Research

Cited by 130

A Genomic Comparison of in vivo and in vitro Brain Microvascular Endothelial Cells

Calabria, A. R., & Shusta, E. V. (2008) · Journal of Cerebral Blood Flow & Metabolism

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 109

Cryopreservation of Brain Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Is Enhanced by Rho-Associated Coiled Coil-Containing Kinase Inhibition

Wilson, H. K., Faubion, M. G., Hjortness, M. K., Palecek, S. P., & Shusta, E. V. (2016) · Tissue Engineering Part C: Methods

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 29

Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood–Brain Barrier

McCloskey, M. C., Ahmad, S. D., Widom, L. P., Kasap, P., Gastfriend, B. D., Shusta, E. V., Palecek, S. P., Engelhardt, B., Gaborski, T. R., Flax, J., et al. (2024) · Biomaterials Research

Barrier Structure and Function Studies3D Printing in Biomedical Research

Cited by 16