Stewart, Sheila A.

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., et al. (2020) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 3,863

Unmasking senescence: context-dependent effects of SASP in cancer

Faget, D. V., Ren, Q., & Stewart, S. A. (2019) · Nature Reviews Cancer

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 863

Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

Mogilenko, D. A., Shpynov, O., Andhey, P. S., Arthur, L., Swain, A., Esaulova, E., Brioschi, S., Shchukina, I., Kerndl, M., Bambouskova, M., et al. (2021) · Immunity

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 683

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

Ruhland, M. K., Loza, A. J., Capietto, A.-H., Luo, X., Knolhoff, B. L., Flanagan, K. C., Belt, B. A., Alspach, E., Leahy, K., Luo, J., et al. (2016) · Nature Communications

Telomeres, Telomerase, and SenescenceImmune cells in cancer

Cited by 496

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

Stewart, S. A., Hahn, W. C., O'Connor, B. F., Banner, E. N., Lundberg, A. S., Modha, P., Mizuno, H., Brooks, M. W., Fleming, M., Zimonjic, D. B., et al. (2002) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 431

Erosion of the telomeric single-strand overhang at replicative senescence

Stewart, S. A., Ben-Porath, I., Carey, V. J., O'Connor, B. F., Hahn, W. C., & Weinberg, R. A. (2003) · Nature Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 335

The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase

Johnson, F. B., Marciniak, R. A., McVey, M., Stewart, S. A., Hahn, W. C., & Guarente, L. (2001) · The EMBO Journal

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 269

Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression

Pazolli, E., Alspach, E., Milczarek, A., Prior, J., Piwnica-Worms, D., & Stewart, S. A. (2012) · Cancer Research

Telomeres, Telomerase, and SenescenceHistone Deacetylase Inhibitors Research

Cited by 192

p38MAPK plays a crucial role in stromal-mediated tumorigenesis

Alspach, E., Flanagan, K. C., Luo, X., Ruhland, M. K., Huang, H., Pazolli, E., Donlin, M. J., Marsh, T., Piwnica-Worms, D., Monahan, J., et al. (2014) · Cancer Discovery

Telomeres, Telomerase, and SenescenceTGF-β signaling in diseases

Cited by 167

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development

Luo, X., Fu, Y., Loza, A. J., Murali, B., Leahy, K. M., Ruhland, M. K., Gang, M., Su, X., Zamani, A., Shi, Y., et al. (2016) · Cell Reports

Bone health and treatmentsTelomeres, Telomerase, and Senescence

Cited by 141

Therapy-Induced Senescence Drives Bone Loss

Yao, Z., Murali, B., Ren, Q., Luo, X., Faget, D. V., Cole, T., Ricci, B., Thotala, D., Monahan, J., van Deursen, J. M., et al. (2020) · Cancer Research

Telomeres, Telomerase, and SenescenceBone health and treatments

Cited by 129

Telomerase Maintains Telomere Structure in Normal Human Cells

Masutomi, K., Yu, E. Y., Khurts, S., Ben-Porath, I., Currier, J. L., Metz, G. B., Brooks, M. W., Kaneko, S., Murakami, S., DeCaprio, J. A., et al. (2003) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 70

Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss

Murali, B., Ren, Q., Luo, X., Faget, D. V., Wang, C., Johnson, R. M., Gruosso, T., Flanagan, K. C., Fu, Y., Leahy, K., et al. (2018) · Cancer Research

Cancer Cells and MetastasisBone health and treatments

Cited by 67

Senescence and the Pro-tumorigenic Stroma

Alspach, E., Fu, Y., & Stewart, S. A. (2013) · Critical Reviews in Oncogenesis

Telomeres, Telomerase, and SenescenceTGF-β signaling in diseases

Cited by 47

Cellular senescence in human liver under normal aging and cancer

Karpova, A., Li, X., Peng, C.-W., Gallant, K. L., Rapp, D. R., Alligood, D. M., Houston, A. J., Park, A., Targino da Costa, A. L. N., Chou, W.-H., et al. (2026) · Cell Genomics

Telomeres, Telomerase, and SenescenceLiver physiology and pathology

Cited by 13