Allgayer, Heike

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

Asangani, I. A., Rasheed, S. A. K., Nikolova, D. A., Leupold, J. H., Colburn, N. H., Post, S., & Allgayer, H. (2008) · Oncogene

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 1,882

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer

Mudduluru, G., George-William, J. N., Muppala, S., Asangani, I. A., Kumarswamy, R., Nelson, L. D., & Allgayer, H. (2011) · Bioscience Reports

Curcumin's Biomedical ApplicationsMicroRNA in disease regulation

Cited by 332

Activation of Src kinase in primary colorectal carcinoma: An indicator of poor clinical prognosis

Allgayer, H., Boyd, D. D., Heiss, M. M., Abdalla, E. K., Curley, S. A., & Gallick, G. E. (2002) · Cancer

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

Cited by 251

Loss of programmed cell death 4 expression marks adenoma‐carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer

Mudduluru, G., Medved, F., Grobholz, R., Jost, C., Gruber, A., Leupold, J. H., Post, S., Jansen, A., Colburn, N. H., & Allgayer, H. (2007) · Cancer

Cell death mechanisms and regulationGenetic factors in colorectal cancer

Cited by 196

Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors

Leupold, J. H., Yang, H.-S., Colburn, N. H., Asangani, I., Post, S., & Allgayer, H. (2007) · Oncogene

Protease and Inhibitor MechanismsMechanisms of cancer metastasis

Cited by 163

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

Ishaque, N., Abba, M. L., Hauser, C., Patil, N., Paramasivam, N., Huebschmann, D., Leupold, J. H., Balasubramanian, G. P., Kleinheinz, K., Toprak, U. H., et al. (2018) · Nature Communications

Cancer Genomics and DiagnosticsColorectal Cancer Treatments and Studies

Cited by 132

Epithelial-to-mesenchymal transition (EMT) and cancer metastasis: the status quo of methods and experimental models 2025

Allgayer, H., Mahapatra, S., Mishra, B., Swain, B., Saha, S., Khanra, S., Kumari, K., Panda, V. K., Malhotra, D., Patil, N. S., et al. (2025) · Molecular Cancer

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 127

Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells

Wang, Q., Sun, Z. X., Allgayer, H., & Yang, H. S. (2010) · Oncogene

Wnt/β-catenin signaling in development and cancerMechanisms of cancer metastasis

Cited by 89

Promoter cloning and characterization of the human programmed cell death protein 4 (pdcd4) gene: evidence for ZBP-89 and Sp-binding motifs as essential Pdcd4 regulators

Leupold, J. H., Asangani, I. A., Mudduluru, G., & Allgayer, H. (2012) · Bioscience Reports

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 23