Chang, Yun C.

Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

Sionov, E., Lee, H., Chang, Y. C., & Kwon-Chung, K. J. (2010) · PLoS Pathogens

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 479

Impaired Host Defense, Hematopoiesis, Granulomatous Inflammation and Type 1–Type 2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1

Gao, J.-L., Wynn, T. A., Chang, Y., Lee, E. J., Broxmeyer, H. E., Cooper, S., Tiffany, H. L., Westphal, H., Kwon-Chung, J., & Murphy, P. M. (1997) · The Journal of Experimental Medicine

Chemokine receptors and signalingInflammation biomarkers and pathways

Cited by 441

A Developmentally Regulated Gene Cluster Involved in Conidial Pigment Biosynthesis in Aspergillus fumigatus

Tsai, H.-F., Wheeler, M. H., Chang, Y. C., & Kwon-Chung, K. J. (1999) · Journal of Bacteriology

Fungal and yeast genetics researchMicrobial Metabolism and Applications

Cited by 385

Gliotoxin Is a Virulence Factor of Aspergillus fumigatus : gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone

Sugui, J. A., Pardo, J., Chang, Y. C., Zarember, K. A., Nardone, G., Galvez, E. M., Müllbacher, A., Gallin, J. I., Simon, M. M., & Kwon-Chung, K. J. (2007) · Eukaryotic Cell

Antifungal resistance and susceptibilityMycotoxins in Agriculture and Food

Cited by 242

Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans

Chang, Y. C., Bien, C. M., Lee, H., Espenshade, P. J., & Kwon‐Chung, K. J. (2007) · Molecular Microbiology

Fungal Infections and StudiesFungal and yeast genetics research

Cited by 212

Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells

Chen, S. H. M., Stins, M. F., Huang, S.-H., Chen, Y. H., Kwon-Chung, K. J., Chang, Y., Kim, K. S., Suzuki, K., & Jong, A. Y. (2003) · Journal of Medical Microbiology

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 189

Heteroresistance to Fluconazole in Cryptococcus neoformans Is Intrinsic and Associated with Virulence

Sionov, E., Chang, Y. C., Garraffo, H. M., & Kwon-Chung, K. J. (2009) · Antimicrobial Agents and Chemotherapy

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 179

Pentaketide Melanin Biosynthesis in Aspergillus fumigatus Requires Chain-length Shortening of a Heptaketide Precursor

Tsai, H.-F., Fujii, I., Watanabe, A., Wheeler, M. H., Chang, Y. C., Yasuoka, Y., Ebizuka, Y., & Kwon-Chung, K. J. (2001) · Journal of Biological Chemistry

Microbial Natural Products and BiosynthesisMicrobial Metabolism and Applications

Cited by 144

Cryptococcus neoformans-Derived Microvesicles Enhance the Pathogenesis of Fungal Brain Infection

Huang, S.-H., Wu, C.-H., Chang, Y. C., Kwon-Chung, K. J., Brown, R. J., & Jong, A. (2012) · PLoS ONE

Fungal Infections and StudiesExtracellular vesicles in disease

Cited by 125

Identification and Characterization of CPS1 as a Hyaluronic Acid Synthase Contributing to the Pathogenesis of Cryptococcus neoformans Infection

Jong, A., Wu, C.-H., Chen, H.-M., Luo, F., Kwon-Chung, K. J., Chang, Y. C., LaMunyon, C. W., Plaas, A., & Huang, S.-H. (2007) · Eukaryotic Cell

Fungal Infections and StudiesProteoglycans and glycosaminoglycans research

Cited by 113

Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells

Jong, A., Wu, C.-H., Shackleford, G. M., Kwon-Chung, K. J., Chang, Y. C., Chen, H.-M., Ouyang, Y., & Huang, S.-H. (2008) · Cellular Microbiology

Fungal Infections and StudiesProteoglycans and glycosaminoglycans research

Cited by 112

Azole heteroresistance in Cryptococcus neoformans: Emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatment

Sionov, E., Chang, Y. C., & Kwon-Chung, K. J. (2013) · Antimicrobial Agents and Chemotherapy

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 112

Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans

Singh, A., Panting, R. J., Varma, A., Saijo, T., Waldron, K. J., Jong, A., Ngamskulrungroj, P., Chang, Y. C., Rutherford, J. C., & Kwon-Chung, K. J. (2013) · mBio

Fungal Infections and StudiesFungal and yeast genetics research

Cited by 108

Hydrolytic Polyketide Shortening by Ayg1p, a Novel Enzyme Involved in Fungal Melanin Biosynthesis

Fujii, I., Yasuoka, Y., Tsai, H.-F., Chang, Y. C., Kwon-Chung, K. J., & Ebizuka, Y. (2004) · Journal of Biological Chemistry

Microbial Natural Products and BiosynthesisMicrobial Metabolism and Applications

Cited by 105

Hyaluronic Acid Receptor CD44 Deficiency Is Associated with Decreased Cryptococcus neoformans Brain Infection

Jong, A., Wu, C.-H., Gonzales-Gomez, I., Kwon-Chung, K. J., Chang, Y. C., Tseng, H.-K., Cho, W.-L., & Huang, S.-H. (2012) · Journal of Biological Chemistry

Fungal Infections and StudiesProteoglycans and glycosaminoglycans research

Cited by 100

Invasion of Cryptococcus neoformans into Human Brain Microvascular Endothelial Cells Is Mediated through the Lipid Rafts-Endocytic Pathway via the Dual Specificity Tyrosine Phosphorylation-regulated Kinase 3 (DYRK3)

Huang, S.-H., Long, M., Wu, C.-H., Kwon-Chung, K. J., Chang, Y. C., Chi, F., Lee, S., & Jong, A. (2011) · Journal of Biological Chemistry

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 69

Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C-α activation

Jong, A., Wu, C.-H., Prasadarao, N. V., Kwon-Chung, K. J., Chang, Y. C., Ouyang, Y., Shackleford, G. M., & Huang, S.-H. (2008) · Cellular Microbiology

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 63

Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans

Ngamskulrungroj, P., Chang, Y., Hansen, B., Bugge, C., Fischer, E., & Kwon-Chung, K. J. (2012) · PLoS ONE

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 56

Efficacy of Olorofim (F901318) against Aspergillus fumigatus , A. nidulans , and A. tanneri in Murine Models of Profound Neutropenia and Chronic Granulomatous Disease

Seyedmousavi, S., Chang, Y. C., Law, D., Birch, M., Rex, J. H., & Kwon-Chung, K. J. (2019) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 56

Cryptococcus neoformans Activates RhoGTPase Proteins Followed by Protein Kinase C, Focal Adhesion Kinase, and Ezrin to Promote Traversal across the Blood-Brain Barrier

Kim, J.-C., Crary, B., Chang, Y. C., Kwon-Chung, K. J., & Kim, K. J. (2012) · Journal of Biological Chemistry

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 47

Cryptococcus neoformans, Unlike Candida albicans, Forms Aneuploid Clones Directly from Uninucleated Cells under Fluconazole Stress

Chang, Y. C., Khanal Lamichhane, A., & Kwon-Chung, K. J. (2018) · mBio

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 34

Exogenous Stimulation of Type I Interferon Protects Mice with Chronic Granulomatous Disease from Aspergillosis through Early Recruitment of Host-Protective Neutrophils into the Lung

Seyedmousavi, S., Davis, M. J., Sugui, J. A., Pinkhasov, T., Moyer, S., Salazar, A. M., Chang, Y. C., & Kwon-Chung, K. J. (2018) · mBio

Antifungal resistance and susceptibilityImmunodeficiency and Autoimmune Disorders

Cited by 17

Cryptococcal Yeast Cells Invade the Central Nervous System via Transcellular Penetration of the Blood-Brain Barrier

Chang, Y. C., Stins, M. F., McCaffery, M. J., Miller, G. F., Pare, D. R., Dam, T., Paul-Satyaseela, M., Kim, K. S., & Kwon-Chung, K. J. (2004) · Infection and Immunity

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 16