Tanguay, Robert M.

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I

Overturf, K., Al-Dhalimy, M., Tanguay, R., Brantly, M., Ou, C.-N., Finegold, M., & Grompe, M. (1996) · Nature Genetics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 549

A Single Mutation of the Fumarylacetoacetate Hydrolase Gene in French Canadians with Hereditary Tyrosinemia Type I

Grompe, M., St.-Louis, M., Demers, S. I., Al-Dhalimy, M., Leclerc, B., & Tanguay, R. M. (1994) · New England Journal of Medicine

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 135

Type 1 hereditary tyrosinemia. Evidence for molecular heterogeneity and identification of a causal mutation in a French Canadian patient.

Phaneuf, D., Lambert, M., Laframboise, R., Mitchell, G., Lettre, F., & Tanguay, R. M. (1992) · Journal of Clinical Investigation

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 84

Rescue of mice homozygous for lethal albino deletions: implications for an animal model for the human liver disease tyrosinemia type 1.

Kelsey, G., Ruppert, S., Beermann, F., Grund, C., Tanguay, R. M., & Schutz, G. (1993) · Genes & Development

Metabolism and Genetic Disordersmelanin and skin pigmentation

Cited by 70

Frequent mutation reversion inversely correlates with clinical severity in a genetic liver disease, hereditary tyrosinemia

Demers, S. I., Russo, P., Lettre, F., & Tanguay, R. M. (2003) · Human Pathology

Metabolism and Genetic DisordersPediatric Hepatobiliary Diseases and Treatments

Cited by 67

Identification of a stop mutation in five Finnish patients suffering from hereditary tyrosinemia type I

St-Louis, M., Leclerc, B., Laine, J., K.Salo, M., Holmberg, C., & Tanguay, R. M. (1994) · Human Molecular Genetics

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 50

Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah−/− knockout mice model

Orejuela, D., Jorquera, R., Bergeron, A., Finegold, M. J., & Tanguay, R. M. (2008) · Journal of Hepatology

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 34