Bonner, Julia Maeve

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

Sienski, G., Narayan, P., Bonner, J. M., Kory, N., Boland, S., Arczewska, A. A., Ralvenius, W. T., Akay, L., Lockshin, E., He, L., et al. (2021) · Science Translational Medicine

Alzheimer's disease research and treatmentsLipid metabolism and biosynthesis

Cited by 336

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Blanchard, J. W., Bula, M., Davila-Velderrain, J., Akay, L. A., Zhu, L., Frank, A., Victor, M. B., Bonner, J. M., Mathys, H., Lin, Y.-T., et al. (2020) · Nature Medicine

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 283

Nanoparticle-mediated delivery of anti-PU.1 siRNA via localized intracisternal administration reduces neuroinflammation

Ralvenius, W. T., Andresen, J. L., Huston, M. M., Penney, J., Bonner, J. M., Fenton, O. S., Langer, R., & Tsai, L. (2024) · Advanced Materials

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 78

PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

Narayan, P., Sienski, G., Bonner, J. M., Lin, Y.-T., Seo, J., Baru, V., Haque, A., Milo, B., Akay, L. A., Graziosi, A., et al. (2020) · Cell Reports

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 75

ABCA7 variants impact phosphatidylcholine and mitochondria in neurons

von Maydell, D., Wright, S. E., Pao, P.-C., Staab, C., King, O., Spitaleri, A., Bonner, J. M., Liu, L., Yu, C. J., Chiu, C.-C., et al. (2025) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 35