Garvie, Colin W.

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Corsello, S. M., Nagari, R. T., Spangler, R. D., Rossen, J., Kocak, M., Bryan, J. G., Humeidi, R., Peck, D., Wu, X., Tang, A. A., et al. (2020) · Nature Cancer

Computational Drug Discovery MethodsCancer Cells and Metastasis

Cited by 878

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Graves, B., Thompson, T., Xia, M., Janson, C., Lukacs, C., Deo, D., Di Lello, P., Fry, D., Garvie, C., Huang, K.-S., et al. (2012) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 230

Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships

Garvie, C. W., Pufall, M. A., Graves, B. J., & Wolberger, C. (2002) · Journal of Biological Chemistry

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 86

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

Garvie, C. W., Wu, X., Papanastasiou, M., Lee, S., Fuller, J., Schnitzler, G. R., Horner, S. W., Baker, A., Zhang, T., Mullahoo, J. P., et al. (2021) · Nature Communications

Phosphodiesterase function and regulationProtein Tyrosine Phosphatases

Cited by 85

Highly Cooperative Recruitment of Ets-1 and Release of Autoinhibition by Pax5

Fitzsimmons, D., Lukin, K., Lutz, R., Garvie, C. W., Wolberger, C., & Hagman, J. (2009) · Journal of Molecular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 25