Janssens, Hettie M.

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Dekkers, J. F., Wiegerinck, C. L., de Jonge, H. R., Bronsveld, I., Janssens, H. M., de Winter-de Groot, K. M., Brandsma, A. M., de Jong, N. W. M., Bijvelds, M. J. C., Scholte, B. J., et al. (2013) · Nature Medicine

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 999

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Dekkers, J. F., Berkers, G., Kruisselbrink, E., Vonk, A., de Jonge, H. R., Janssens, H. M., Bronsveld, I., van de Graaf, E. A., Nieuwenhuis, E. E. S., Houwen, R. H. J., et al. (2016) · Science Translational Medicine

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 548

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Berkers, G., van Mourik, P., Vonk, A. M., Kruisselbrink, E., Dekkers, J. F., de Winter-de Groot, K. M., Arets, H. G. M., Marck-van der Wilt, R. E. P., Dijkema, J. S., Vanderschuren, M. M., et al. (2019) · Cell Reports

Cystic Fibrosis Research AdvancesTissue Engineering and Regenerative Medicine

Cited by 310

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Geurts, M. H., de Poel, E., Amatngalim, G. D., Oka, R., Meijers, F. M., Kruisselbrink, E., van Mourik, P., Berkers, G., de Winter-de Groot, K. M., Michel, S., et al. (2020) · Cell Stem Cell

CRISPR and Genetic EngineeringCystic Fibrosis Research Advances

Cited by 222

Development of the Nasopharyngeal Microbiota in Infants with Cystic Fibrosis

Prevaes, S. M. P. J., de Winter-de Groot, K. M., Janssens, H. M., de Steenhuijsen Piters, W. A. A., Tramper-Stranders, G. A., Wyllie, A. L., Hasrat, R., Tiddens, H. A., van Westreenen, M., van der Ent, C. K., et al. (2016) · American Journal of Respiratory and Critical Care Medicine

Cystic Fibrosis Research AdvancesBacterial biofilms and quorum sensing

Cited by 131

rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice

Vidović, D., Carlon, M. S., da Cunha, M. F., Dekkers, J. F., Hollenhorst, M. I., Bijvelds, M. J. C., Ramalho, A. S., Van den Haute, C., Ferrante, M., Baekelandt, V., et al. (2016) · American Journal of Respiratory and Critical Care Medicine

Cystic Fibrosis Research AdvancesVirus-based gene therapy research

Cited by 74

Change in nutrient and dietary intake in European children with cystic fibrosis after a 6-month intervention with a self-management mHealth tool

Calvo-Lerma, J., Boon, M., Hulst, J., Colombo, C., Asseiceira, I., Garriga, M., Masip, E., Claes, I., Bulfamante, A., Janssens, H. M., et al. (2021) · Nutrients

Mobile Health and mHealth ApplicationsCystic Fibrosis Research Advances

Cited by 14