Ruffini, Francesca

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

Verderio, C., Muzio, L., Turola, E., Bergami, A., Novellino, L., Ruffini, F., Riganti, L., Corradini, I., Francolini, M., Garzetti, L., et al. (2012) · Annals of Neurology

Multiple Sclerosis Research StudiesExtracellular vesicles in disease

Cited by 326

Convergence between microglia and peripheral macrophages phenotype during development and neuroinflammation

Grassivaro, F., Menon, R., Acquaviva, M., Ottoboni, L., Ruffini, F., Bergamaschi, A., Muzio, L., Farina, C., & Martino, G. (2020) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 127

iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF

Laterza, C., Merlini, A., De Feo, D., Ruffini, F., Menon, R., Onorati, M., Fredrickx, E., Muzio, L., Lombardo, A., Comi, G., et al. (2013) · Nature Communications

Multiple Sclerosis Research StudiesPluripotent Stem Cells Research

Cited by 121

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis

Starost, L., Lindner, M., Herold, M., Xu, Y. K. T., Drexler, H. C. A., Heß, K., Ehrlich, M., Ottoboni, L., Ruffini, F., Stehling, M., et al. (2020) · Acta Neuropathologica

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 79

Neural Stem Cells of the Subventricular Zone Contribute to Neuroprotection of the Corpus Callosum after Cuprizone-Induced Demyelination

Butti, E., Bacigaluppi, M., Chaabane, L., Ruffini, F., Brambilla, E., Berera, G., Montonati, C., Quattrini, A., & Martino, G. (2019) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 67

Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration

Colombo, E., Bassani, C., De Angelis, A., Ruffini, F., Ottoboni, L., Comi, G., Martino, G., & Farina, C. (2020) · Frontiers in Immunology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 66

Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids

Fagiani, F., Pedrini, E., Martire, M. S., Gastoldi, G., Vanden Bulcke, C., Lin, J.-P., Maric, D., Brambilla, E., Ruffini, F., Peri, C., et al. (2025) · Nature Communications

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 19