Wulff, Heike

A non-hallucinogenic psychedelic analogue with therapeutic potential

Cameron, L. P., Tombari, R. J., Lu, J., Pell, A. J., Hurley, Z. Q., Ehinger, Y., Vargas, M. V., McCarroll, M. N., Taylor, J. C., Myers-Turnbull, D., et al. (2021) · Nature

Psychedelics and Drug StudiesAlkaloids: synthesis and pharmacology

Cited by 473

An artificial intelligence accelerated virtual screening platform for drug discovery

Zhou, G., Rusnac, D.-V., Park, H., Canzani, D., Nguyen, H. M., Stewart, L., Bush, M. F., Nguyen, P. T., Wulff, H., Yarov-Yarovoy, V., et al. (2024) · Nature Communications

Computational Drug Discovery Methodsvaccines and immunoinformatics approaches

Cited by 260

Differential Kv1.3, KCa3.1, and Kir2.1 expression in “classically” and “alternatively” activated microglia

Nguyen, H. M., Grössinger, E. M., Horiuchi, M., Davis, K. W., Jin, L., Maezawa, I., & Wulff, H. (2017) · Glia

Neuroinflammation and Neurodegeneration MechanismsIon channel regulation and function

Cited by 178

Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer’s disease: preclinical proof of concept

Maezawa, I., Nguyen, H. M., Di Lucente, J., Jenkins, D. P., Singh, V., Hilt, S., Kim, K., Rangaraju, S., Levey, A. I., Wulff, H., et al. (2018) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 125

The voltage‐gated potassium channel Kv1.3 is required for microglial pro‐inflammatory activation in vivo

Di Lucente, J., Nguyen, H. M., Wulff, H., Jin, L., & Maezawa, I. (2018) · Glia

Neuroinflammation and Neurodegeneration MechanismsIon channel regulation and function

Cited by 96

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

Chhabra, S., Chang, S. C., Nguyen, H. M., Huq, R., Tanner, M. R., Londono, L. M., Estrada, R., Dhawan, V., Chauhan, S., Upadhyay, S. K., et al. (2014) · The FASEB Journal

Parasites and Host InteractionsIon channel regulation and function

Cited by 91

A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes

Beeton, C., Wulff, H., Singh, S., Botsko, S., Crossley, G., Gutman, G. A., Cahalan, M. D., Pennington, M., & Chandy, K. G. (2003) · Journal of Biological Chemistry

Ion channel regulation and functionIon Channels and Receptors

Cited by 90

Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity

Jin, L.-W., Horiuchi, M., Wulff, H., Liu, X.-B., Cortopassi, G. A., Erickson, J. D., & Maezawa, I. (2015) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 88