Weinstock, David M.

Next-generation characterization of the Cancer Cell Line Encyclopedia

Ghandi, M., Huang, F. W., Jané-Valbuena, J., Kryukov, G. V., Lo, C. C., McDonald, E. R., Barretina, J., Gelfand, E. T., Bielski, C. M., Li, H., et al. (2019) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,394

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 295

Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma

Horwitz, S. M., Koch, R., Porcu, P., Oki, Y., Moskowitz, A., Perez, M., Myskowski, P., Officer, A., Jaffe, J. D., Morrow, S. N., et al. (2018) · Blood

Lymphoma Diagnosis and TreatmentChronic Lymphocytic Leukemia Research

Cited by 290

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays

Cermak, N., Olcum, S., Delgado, F. F., Wasserman, S. C., Payer, K. R., A Murakami, M., Knudsen, S. M., Kimmerling, R. J., Stevens, M. M., Kikuchi, Y., et al. (2016) · Nature Biotechnology

Microfluidic and Bio-sensing TechnologiesMicrofluidic and Capillary Electrophoresis Applications

Cited by 227

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

Xu, Y., Sun, Y., Jiang, X., Ayrapetov, M. K., Moskwa, P., Yang, S., Weinstock, D. M., & Price, B. D. (2010) · Journal of Cell Biology

DNA Repair MechanismsChromatin Remodeling and Cancer

Cited by 194

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

Dobrovolsky, D., Wang, E. S., Morrow, S., Leahy, C., Faust, T., Nowak, R. P., Donovan, K. A., Yang, G., Li, Z., Fischer, E. S., et al. (2019) · Blood

Protein Degradation and InhibitorsChronic Lymphocytic Leukemia Research

Cited by 169

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

He, Y., Koch, R., Budamagunta, V., Zhang, P., Zhang, X., Khan, S., Thummuri, D., Ortiz, Y. T., Zhang, X., Lv, D., et al. (2020) · Journal of Hematology & Oncology

Protein Degradation and InhibitorsCell death mechanisms and regulation

Cited by 139

B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies

Xiao, G., Chan, L. N., Klemm, L., Braas, D., Chen, Z., Geng, H., Zhang, Q. C., Aghajanirefah, A., Cosgun, K. N., Sadras, T., et al. (2018) · Cell

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 129

First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation

Dainiak, N., Gent, R. N., Carr, Z., Schneider, R., Bader, J., Buglova, E., Chao, N., Coleman, C. N., Ganser, A., Gorin, C., et al. (2011) · Disaster Medicine and Public Health Preparedness

Effects of Radiation ExposureDisaster Response and Management

Cited by 107

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

Stevens, M. M., Maire, C. L., Chou, N., Murakami, M. A., Knoff, D. S., Kikuchi, Y., Kimmerling, R. J., Liu, H., Haidar, S., Calistri, N. L., et al. (2016) · Nature Biotechnology

Microfluidic and Bio-sensing TechnologiesCancer Cells and Metastasis

Cited by 106

The public repository of xenografts enables discovery and randomized phase II-like trials in mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 80

Health Care System Planning for and Response to a Nuclear Detonation

Hick, J. L., Weinstock, D. M., Coleman, C. N., Hanfling, D., Cantrill, S., Redlener, I., Bader, J. L., Murrain-Hill, P., & Knebel, A. R. (2011) · Disaster Medicine and Public Health Preparedness

Disaster Response and ManagementNuclear Issues and Defense

Cited by 49

HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma

Jacobson, C., Kopp, N., Layer, J. V., Redd, R. A., Tschuri, S., Haebe, S., van Bodegom, D., Bird, L., Christie, A. L., Christodoulou, A., et al. (2016) · Blood

Lymphoma Diagnosis and TreatmentChronic Lymphocytic Leukemia Research

Cited by 45

A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia

Harada, T., Heshmati, Y., Kalfon, J., Ferrucio, J. X., Perez, M., Ewers, J., Kossenkov, A., Ellegast, J. M., Yi, J. S., Bowker, A., et al. (2021) · Genes & Development

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 31

The MDM2 Inhibitor NVP-CGM097 Is Highly Active in a Randomized Preclinical Trial of B-Cell Acute Lymphoblastic Leukemia Patient Derived Xenografts

Townsend, E. C., DeSouza, T., Murakami, M. A., Montero, J., Stevenson, K., Christie, A. L., Christodolou, A. N., Vojinovic, U., Kopp, N., Barzaghi-Rinaudo, P., et al. (2015) · Blood

Acute Lymphoblastic Leukemia researchCancer-related Molecular Pathways

Cited by 10