Yuan, Tanglong

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Zuo, E., Sun, Y., Wei, W., Yuan, T., Ying, W., Sun, H., Yuan, L., Steinmetz, L. M., Li, Y., & Yang, H. (2019) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 782

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Xu, C., Zhou, Y., Xiao, Q., He, B., Geng, G., Wang, Z., Cao, B., Dong, X., Bai, W., Wang, Y., et al. (2021) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 351

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

Yuan, T., Yan, N., Fei, T., Zheng, J., Meng, J., Li, N., Liu, J., Zhang, H., Xie, L., Ying, W., et al. (2021) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 55

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Li, G., Dong, X., Luo, J., Yuan, T., Li, T., Zhao, G., Zhang, H., Zhou, J., Zeng, Z., Cui, S., et al. (2024) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 9