Hewitt, Nicola J.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

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Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies

Hewitt, N. J., Gómez Lechón, M. J., Houston, J. B., Hallifax, D., Brown, H. S., Maurel, P., Kenna, J. G., Gustavsson, L., Lohmann, C., Skonberg, C., et al. (2007) · Drug Metabolism Reviews

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

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The Use of Toxicokinetic Information for Setting Concentrations of In Vitro Toxicity Tests and for Interpreting Their Results: A Proposed Workflow

Landsiedel, R., Birk, B., Demuth, P., Fabian, E., Hewitt, N. J., Hollnagel, H. M., & Scheel, J. (2024) · Applied In Vitro Toxicology

Animal testing and alternativesCarcinogens and Genotoxicity Assessment

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