Gentleman, Susan

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle

Redmond, T. M., Poliakov, E., Yu, S., Tsai, J.-Y., Lu, Z., & Gentleman, S. (2005) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 409

RPE65 Is an Iron(II)-dependent Isomerohydrolase in the Retinoid Visual Cycle

Moiseyev, G., Takahashi, Y., Chen, Y., Gentleman, S., Redmond, T. M., Crouch, R. K., & Ma, J.-X. (2006) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 119

RPE65, Visual Cycle Retinol Isomerase, Is Not Inherently 11-cis-specific

Redmond, T. M., Poliakov, E., Kuo, S., Chander, P., & Gentleman, S. (2010) · Journal of Biological Chemistry

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 65

Aromatic Residues in the Substrate Cleft of RPE65 Protein Govern Retinol Isomerization and Modulate Its Progression

Chander, P., Gentleman, S., Poliakov, E., & Redmond, T. M. (2012) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 19

Aromatic Lipophilic Spin Traps Effectively Inhibit RPE65 Isomerohydrolase Activity

Poliakov, E., Parikh, T., Ayele, M., Kuo, S., Chander, P., Gentleman, S., & Redmond, T. M. (2011) · Biochemistry

Electron Spin Resonance StudiesRetinal Development and Disorders

Cited by 18