Botto, Marina

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

Garlanda, C., Hirsch, E., Bozza, S., Salustri, A., De Acetis, M., Nota, R., Maccagno, A., Riva, F., Bottazzi, B., Peri, G., et al. (2002) · Nature

Biomarkers in Disease MechanismsImmune Response and Inflammation

Cited by 669

The Role of Complement in the Development of Systemic Lupus Erythematosus

Manderson, A. P., Botto, M., & Walport, M. J. (2004) · Annual Review of Immunology

Systemic Lupus Erythematosus ResearchComplement system in diseases

Cited by 538

Absence of C1q Leads to Less Neuropathology in Transgenic Mouse Models of Alzheimer's Disease

Fonseca, M. I., Zhou, J., Botto, M., & Tenner, A. J. (2004) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 345

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

Naito, A. T., Sumida, T., Nomura, S., Liu, M.-L., Higo, T., Nakagawa, A., Okada, K., Sakai, T., Hashimoto, A., Hara, Y., et al. (2012) · Cell

Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms

Cited by 320

Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene

Botto, M., Hawkins, P. N., Bickerstaff, M. C. M., Herbert, J., Bygrave, A. E., Mcbride, A., Hutchinson, W. L., Tennent, G. A., Walportz, M. J., & Pepys, M. B. (1997) · Nature Medicine

Amyloidosis: Diagnosis, Treatment, OutcomesAlzheimer's disease research and treatments

Cited by 266

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

Clarke, A. J., Ellinghaus, U., Cortini, A., Stranks, A., Simon, A. K., Botto, M., & Vyse, T. J. (2015) · Annals of the Rheumatic Diseases

Systemic Lupus Erythematosus ResearchAutophagy in Disease and Therapy

Cited by 252

C1q restrains autoimmunity and viral infection by regulating CD8 + T cell metabolism

Ling, G. S., Crawford, G., Buang, N., Bartok, I., Tian, K., Thielens, N. M., Bally, I., Harker, J. A., Ashton-Rickardt, P. G., Rutschmann, S., et al. (2018) · Science

Complement system in diseasesSystemic Lupus Erythematosus Research

Cited by 199

Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus

Buang, N., Tapeng, L., Gray, V., Sardini, A., Whilding, C., Lightstone, L., Cairns, T. D., Pickering, M. C., Behmoaras, J., Ling, G. S., et al. (2021) · Nature Communications

Systemic Lupus Erythematosus ResearchT-cell and B-cell Immunology

Cited by 118