Nguyen, Thanh N.

Mitochondrial degradation: Mitophagy and beyond

Uoselis, L., Nguyen, T. N., & Lazarou, M. (2023) · Molecular Cell

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 270

Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function

Ma, S. B., Nguyen, T. N., Tan, I., Ninnis, R., Iyer, S., Stroud, D. A., Menard, M., Kluck, R. M., Ryan, M. T., & Dewson, G. (2014) · Cell Death & Differentiation

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 138

Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

Ren, X., Nguyen, T. N., Lam, W. K., Buffalo, C. Z., Lazarou, M., Yokom, A. L., & Hurley, J. H. (2023) · Science Advances

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 68

Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

Ren, X., Nguyen, T. N., Lam, W. K., Buffalo, C. Z., Lazarou, M., Yokom, A. L., & Hurley, J. H. (2022) · Science Advances

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 68

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery

Adriaenssens, E., Schaar, S., Cook, A. S. I., Stuke, J. F. M., Sawa-Makarska, J., Nguyen, T. N., Ren, X., Schuschnig, M., Romanov, J., Khuu, G., et al. (2025) · Nature Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 53

Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery

Adriaenssens, E., Schaar, S., Cook, A. S. I., Stuke, J. F. M., Sawa-Makarska, J., Nguyen, T. N., Ren, X., Schuschnig, M., Romanov, J., Khuu, G., et al. (2024) · Nature Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 53

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

Chen, M., Nguyen, T. N., Ren, X., Khuu, G., Cook, A. S. I., Zhao, Y., Yildiz, A., Lazarou, M., & Hurley, J. H. (2023) · Nature Structural & Molecular Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 40

Structural pathway for PI3-kinase regulation by VPS15 in autophagy

Cook, A. S. I., Chen, M., Nguyen, T. N., Cabezudo, A. C., Khuu, G., Rao, S., Garcia, S. N., Yang, M., Iavarone, A. T., Ren, X., et al. (2025) · Science

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 34

Interaction of PINK1 with nucleotides and kinetin

Gan, Z. Y., Callegari, S., Nguyen, T. N., Kirk, N. S., Leis, A., Lazarou, M., Dewson, G., & Komander, D. (2024) · Science Advances

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 14