Tatarakis, David

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

van Lengerich, B., Zhan, L., Xia, D., Chan, D., Joy, D., Park, J. I., Tatarakis, D., Calvert, M., Hummel, S., Lianoglou, S., et al. (2023) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 233

Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier

Barker, S. J., Thayer, M. B., Kim, C., Tatarakis, D., Simon, M. J., Dial, R., Nilewski, L., Wells, R. C., Zhou, Y., Afetian, M., et al. (2024) · Science Translational Medicine

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 142

Decreased lipidated ApoE‐receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes

Guo, J. L., Braun, D., Fitzgerald, G. A., Hsieh, Y.-T., Rougé, L., Litvinchuk, A., Steffek, M., Propson, N. E., Heffner, C. M., Discenza, C., et al. (2025) · Cell

Alzheimer's disease research and treatmentsLysosomal Storage Disorders Research

Cited by 91

Lysosomes cell autonomously regulate myeloid cell states and immune responses

Tejwani, L., Balak, C., Skuja, L. L., Tatarakis, D., Rana, A., Fitzgerald, G. A., Ha, C., Lunkes de Melo, G., Sun, E. W., Heffner, C. M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 4