Sareen, Dhruv

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

Sareen, D., O’Rourke, J. G., Meera, P., Muhammad, A. K. M. G., Grant, S., Simpkinson, M., Bell, S., Carmona, S., Ornelas, L., Sahabian, A., et al. (2013) · Science Translational Medicine

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 670

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 423

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

Tam, O. H., Rozhkov, N. V., Shaw, R., Kim, D., Hubbard, I., Fennessey, S., Propp, N., Phatnani, H., Kwan, J., Sareen, D., et al. (2019) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 327

Modeling ALS with motor neurons derived from human induced pluripotent stem cells

Sances, S., Bruijn, L. I., Chandran, S., Eggan, K., Ho, R., Klim, J. R., Livesey, M. R., Lowry, E., Macklis, J. D., Rushton, D., et al. (2016) · Nature Neuroscience

Pluripotent Stem Cells ResearchAmyotrophic Lateral Sclerosis Research

Cited by 289

Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, Lim, R. G., Salazar, L. L., Wilton, D. K., King, A. R., Stocksdale, J. T., Sharifabad, D., Lau, A. L., Stevens, B., Reidling, J. C., et al. (2017) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 221

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

Coyne, A. N., Zaepfel, B. L., Hayes, L., Fitchman, B., Salzberg, Y., Luo, E.-C., Bowen, K., Trost, H., Aigner, S., Rigo, F., et al. (2020) · Neuron

Amyotrophic Lateral Sclerosis ResearchNuclear Structure and Function

Cited by 156

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.

Das Sharma, S., Pal, R., Reddy, B. K., Selvaraj, B. T., Raj, N., Samaga, K. K., Srinivasan, D. J., Ornelas, L., Sareen, D., Livesey, M. R., et al. (2020) · Molecular Autism

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 28