Hashimoto, Shoko

APP mouse models for Alzheimer’s disease preclinical studies.

Sasaguri, H., Nilsson, P., Hashimoto, S., Nagata, K., Saito, T., De Strooper, B., Hardy, J., Vassar, R., Winblad, B., & Saido, T. C. (2017) · The EMBO Journal

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 793

Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation

Saito, T., Mihira, N., Matsuba, Y., Sasaguri, H., Hashimoto, S., Narasimhan, S., Zhang, B., Murayama, S., Higuchi, M., Lee, V. M. Y., et al. (2019) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 248

Recent advances in the modeling of Alzheimer’s disease

Sasaguri, H., Hashimoto, S., Watamura, N., Sato, K., Takamura, R., Nagata, K., Tsubuki, S., Ohshima, T., Yoshiki, A., Sato, K., et al. (2022) · Frontiers in Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 157

Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

Hashimoto, S., & Saido, T. C. (2018) · Open Biology

Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatments

Cited by 129

Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression

Saito, T., Matsuba, Y., Yamazaki, N., Hashimoto, S., & Saido, T. C. (2016) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsCalpain Protease Function and Regulation

Cited by 121

Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells

Shirotani, K., Hori, Y., Yoshizaki, R., Higuchi, E., Colonna, M., Saito, T., Hashimoto, S., Saito, T., Saido, T. C., & Iwata, N. (2019) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 116

Tau binding protein CAPON induces tau aggregation and neurodegeneration

Hashimoto, S., Matsuba, Y., Kamano, N., Mihira, N., Sahara, N., Takano, J., Muramatsu, S.-I., Saido, T. C., & Saito, T. (2019) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 111