Siedlak, Sandra L.

Mitochondrial abnormalities in Alzheimer's disease

Hirai, K., Aliev, G., Nunomura, A., Fujioka, H., Russell, R. L., Atwood, C. S., Johnson, A. B., Kress, Y., Vinters, H. V., Tabaton, M., et al. (2001) · The Journal of Neuroscience

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,367

Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

Wang, X., Su, B., Siedlak, S. L., Moreira, P. I., Fujioka, H., Wang, Y., Casadesus, G., & Zhu, X. (2008) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 835

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., et al. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 280

Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model

Wang, W., Yin, J., Ma, X., Zhao, F., Siedlak, S. L., Wang, Z., Torres, S., Fujioka, H., Xu, Y., Perry, G., et al. (2017) · Human Molecular Genetics

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 175

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

Myung, N.-H., Zhu, X., Kruman, I. I., Castellani, R. J., Petersen, R. B., Siedlak, S. L., Perry, G., Smith, M. A., & Lee, H.-G. (2008) · AGE

Alzheimer's disease research and treatmentsDNA Repair Mechanisms

Cited by 170

Abnormal localization of iron regulatory protein in Alzheimer’s disease

Smith, M. A., Wehr, K., Harris, P. L. R., Siedlak, S. L., Connor, J. R., & Perry, G. (1998) · Brain Research

Iron Metabolism and DisordersAlzheimer's disease research and treatments

Cited by 162

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

Collingwood, J. F., Chong, R. K. K., Kasama, T., Cervera-Gontard, L., Dunin-Borkowski, R. E., Perry, G., Pósfai, M., Siedlak, S. L., Simpson, E. T., Smith, M. A., et al. (2008) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsIron Metabolism and Disorders

Cited by 147

MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons

Wang, W., Zhang, F., Li, L., Tang, F., Siedlak, S. L., Fujioka, H., Liu, Y., Su, B., Pi, Y., & Wang, X. (2015) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 103

Chitin-like Polysaccharides in Alzheimers Disease Brains

Castellani, R., Siedlak, S., Fortino, A., Perry, G., Ghetti, B., & Smith, M. (2005) · Current Alzheimer Research

Alzheimer's disease research and treatmentsStudies on Chitinases and Chitosanases

Cited by 52

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau

HARTZLER, A., ZHU, X., SIEDLAK, S., CASTELLANI, R., AVILA, J., PERRY, G., & SMITH, M. (2002) · Neurobiology of Aging

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 43

The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease

Wang, C., Zhao, F., Shen, K., Wang, W., Siedlak, S. L., Lee, H., Phelix, C. F., Perry, G., Shen, L., Tang, B., et al. (2019) · Brain Pathology

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 18