Skiniotis, Georgios

Crystal structure of the β2 adrenergic receptor–Gs protein complex

Rasmussen, S. G. F., DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., et al. (2011) · Nature

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

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Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Kim, K., Che, T., Panova, O., DiBerto, J. F., Lyu, J., Krumm, B. E., Wacker, D., Robertson, M. J., Seven, A. B., Nichols, D. E., et al. (2020) · Cell

Receptor Mechanisms and SignalingPsychedelics and Drug Studies

Cited by 481

Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Huang, W., Masureel, M., Qu, Q., Janetzko, J., Inoue, A., Kato, H. E., Robertson, M. J., Nguyen, K. C., Glenn, J. S., Skiniotis, G., et al. (2020) · Nature

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 373

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells

Glassman, C. R., Mathiharan, Y. K., Jude, K. M., Su, L., Panova, O., Lupardus, P. J., Spangler, J. B., Ely, L. K., Thomas, C., Skiniotis, G., et al. (2021) · Cell

Cytokine Signaling Pathways and InteractionsImmune Cell Function and Interaction

Cited by 181

Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5

Komolov, K. E., Du, Y., Duc, N. M., Betz, R. M., Rodrigues, J. P. G. L. M., Leib, R. D., Patra, D., Skiniotis, G., Adams, C. M., Dror, R. O., et al. (2017) · Cell

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 152

Architecture of an HIV-1 reverse transcriptase initiation complex

Larsen, K. P., Mathiharan, Y. K., Kappel, K., Coey, A. T., Chen, D.-H., Barrero, D., Madigan, L., Puglisi, J. D., Skiniotis, G., & Puglisi, E. V. (2018) · Nature

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 66

Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor

Batebi, H., Pérez-Hernández, G., Rahman, S. N., Lan, B., Kamprad, A., Shi, M., Speck, D., Tiemann, J. K. S., Guixà-González, R., Reinhardt, F., et al. (2024) · Nature Structural & Molecular Biology

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

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A Putative Binding Model of Nitazene Derivatives at the μ-Opioid Receptor

Clayton, J., Shi, L., Robertson, M. J., Skiniotis, G., Michaelides, M., Stavitskaya, L., & Shen, J. (2025) · Neuropharmacology

Receptor Mechanisms and SignalingComputational Drug Discovery Methods

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