Simpson, Joshua B.

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Foley, M. H., Walker, M. E., Stewart, A. K., O’Flaherty, S., Gentry, E. C., Patel, S., Beaty, V. V., Allen, G., Pan, M., Simpson, J. B., et al. (2023) · Nature Microbiology

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 181

Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome

Edwinson, A. L., Yang, L., Peters, S., Hanning, N., Jeraldo, P., Jagtap, P., Simpson, J. B., Yang, T.-Y., Kumar, P., Mehta, S., et al. (2022) · Nature Microbiology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 105

Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate

Simpson, J. B., Sekela, J. J., Graboski, A. L., Borlandelli, V. B., Barker, N. K., Sorgen, A. A., Bivins, M. M., Mordant, A. L., Johnson, R. L., Bhatt, A. P., et al. (2022) · Gut Microbes

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 45